COVID-19 患者心电图结果的重要性:院内预后的预测因子。
Importance of ECG findings in COVID-19 patients: Predictor of in-hospital prognosis.
发表日期:2024
作者:
Mahsa Behnemoon, Mojhdeh Mehrno, Vahid Alinejad
来源:
DIABETES & METABOLISM
摘要:
COVID-19 患者的心脏损伤导致预后较差。心电图的解释有助于早期诊断可能的心脏受累。在调整其他变量后,我们试图确定入院时的初始心电图是否可以增加额外的预后价值。 在这项单中心横断面研究中,纳入了 2020 年 2 月至 2021 年 11 月期间 1165 名 COVID-19 PCR 呈阳性的患者我们的研究。患者根据入院单位、出院幸存者或非幸存者进行分组。使用单变量分析和逻辑回归模型确定 ICU 入住和院内死亡率的预测因素。平均年龄为 55.6 ± 16.2 岁,其中 52% 为男性。 1165 名患者中,有 149 人(12.8%)在住院期间死亡。窦性心动过速是最常见的心律失常,其次是房性和室性早搏、窦性心动过缓和心房颤动(分别为 28.6%、5.6%、3.9% 和 2.1%)。年龄 (p<0.001)、性别 (p=0.006)、糖尿病史 (p=0.002)、高血压 (p=0.018)、缺血性心脏病 (p=0.004) 和癌症 (p<0.001) 更常见在非幸存者中。在心电图检查结果中,心动过速、低电压 QRS、ST-T 变化和心律失常与死亡风险增加相关。然而,在回归分析中,只有性别(OR 1.89,95% CI 1.2至2.9,p=0.004)、年龄(OR 1.03,95% CI 1.02至1.05,p<0.001)和初始心动过速(OR 1.02,95% CI 1.01至1.03,p<0.001)是院内死亡率的独立预测因子。我们的数据表明,最初的心电图检查结果可能有助于区分入ICU或院内死亡风险增加的患者。
Cardiac injury in COVID-19 patients confers a worse prognosis. The interpretation of electrocardiography can be beneficial in the early diagnosis of probable cardiac involvement. After adjusting for other variables, we sought to determine if the initial ECG on admission could add additional prognostic value.In this single-center cross-sectional study, 1165 patients with a positive COVID-19 PCR between Feb 2020 and Nov 2021 were enrolled in our study. Patients were grouped according to their admitted units, and survivors to hospital discharge or non-survivors. Predictors of ICU admission and in-hospital mortality were determined using univariate analysis and a logistic regression model.The mean age was 55.6 ± 16.2 years and 52% were male. Out of 1165 patients, 149 deaths (12.8%) were recorded during hospitalization. Sinus tachycardia was the most common dysrhythmia, followed by premature atrial and ventricular beats, sinus bradycardia, and atrial fibrillation (28.6%, 5.6%, 3.9%, and 2.1%, respectively). Age (p<0.001), sex (p=0.006), history of diabetes mellitus (p=0.002), hypertension (p=0.018), ischemic heart disease (p=0.004), and cancer (p<0.001) were more frequent among non-survivors. Among ECG findings, tachycardia, low voltage QRS, ST-T changes, and dysrhythmia were related to an increased mortality risk. However, in regression analysis, only sex (OR 1.89, 95% CI 1.2 to 2.9, p=0.004), age (OR 1.03, 95% CI 1.02 to 1.05, p<0.001), and initial tachycardia (OR 1.02, 95% CI 1.01 to 1.03, p<0.001) were independent predictors of in-hospital mortality.Our data suggest that initial electrocardiographic findings could be helpful in distinguishing patients with an increased risk for ICU admission or in-hospital death.