一名 29 岁男性出现上肢 (UE) 和下肢 (LE) 的急性左侧无力，这是睾丸癌的非典型症状，但对于脑转移来说并不罕见。睾丸癌通常表现为睾丸肿块或不适。他的病史包括先前切除的睾丸肿块，由于患者失访，病理结果未知。经检查，他表现出明显的神经功能缺损和多个皮下结节。影像学显示多处增强的脑部病变以及肺部和其他区域的广泛转移。实验室检查显示甲胎蛋白和乳酸脱氢酶水平升高，支持晚期非精原细胞肿瘤的诊断。他接受了多学科治疗，包括地塞米松、左乙拉西坦和化疗。患者对治疗反应良好，神经功能明显改善，病情稳定。该病例强调了转移性睾丸癌的诊断和治疗挑战，特别是皮肤受累等罕见表现，并强调了全面诊断评估和多学科护理的重要性。版权所有 © 2024，Reid 等人。

A 29-year-old male presented with acute left-sided weakness in both the upper extremity (UE) and lower extremity (LE), an atypical symptom for testicular cancer but not uncommon for brain metastasis. Testicular cancer usually manifests as a testicular mass or discomfort. His medical history included a previously resected testicular mass, with pathology results unknown due to the patient being lost to follow-up. Upon examination, he exhibited significant neurological deficits and multiple subcutaneous nodules. Imaging revealed multiple enhancing brain lesions and widespread metastases to the lungs and other regions. Laboratory tests showed elevated alpha-fetoprotein and lactate dehydrogenase levels, supporting a diagnosis of advanced non-seminomatous germ cell tumor. He received multidisciplinary treatment, including dexamethasone, levetiracetam, and chemotherapy. The patient responded well to the treatment, showing significant improvement in neurological function and stabilization of his condition. This case underscores the diagnostic and therapeutic challenges of metastatic testicular cancer, particularly with rare presentations such as cutaneous involvement, and highlights the importance of comprehensive diagnostic evaluations and multidisciplinary care.Copyright © 2024, Reid et al.