COVID-19 大流行导致许多国家的癌症护理发生了前所未有的变化，从多个方面影响了癌症患者的生活。本研究探讨了癌症护理的变化对患者健康相关生活质量 (HRQL) 的影响，这是癌症护理的一个关键结果。该研究旨在评估大流行之前和期间患者自我报告的 HRQL，并确定其身心健康的预测因素。该研究采用了大规模门诊癌症护理 (OCC) 患者体验调查，包括退伍军人 RAND 12-项目健康调查，评估癌症患者在 COVID-19 大流行之前（2020 年 1 月至 5 月）和期间（2021 年 5 月至 7 月）的经历和 HRQL。进行配对 t 检验，以比较大流行之前和期间身体成分评分 (PCS) 和心理成分评分 (MCS) 的差异。采用多变量线性回归研究了大流行期间影响 PCS 和 MCS 的因素（社会人口统计学、临床和患者报告的经历）。大流行期间 PCS 显着下降，而 MCS 保持稳定。较低的 PCS 贡献因素包括年龄较大、更多的远程医疗就诊、自我报告的住院治疗以及自上次癌症诊断以来的时间较长。较高的 PCS 与城市居住、大流行期间较高的 MCS 以及被认为积极的医疗保健提供者 (HCP) 参与相关。对于 MCS，较低的分数与女性性别和更多的远程医疗就诊有关，而较高的分数与白人、受过高等教育、大流行前较高的 MCS 以及认为积极的 HCP 参与有关。OCC 患者体验调查提供了独特的患者级别数据集测量 COVID-19 大流行爆发前后的 HRQL。该研究强调了癌症患者在大流行期间面临的挑战，PCS 显着减少。然而，MCS 的稳定性表明有效的应对机制。社会人口学、临床和远程医疗相关变量在影响 PCS 和 MCS 方面发挥着复杂的作用。感知到的 HCP 参与成为与较高 PCS 和 MCS 相关的关键因素。应对后大流行时代需要采取干预措施，加强患者与提供者的关系，优化医疗支持系统（例如远程医疗服务），并考虑到心理健康对 PCS 和 MCS 的影响，优先考虑心理健康。© 2024。作者。

The COVID-19 pandemic resulted in unprecedented changes to cancer care in many countries, impacting cancer patients' lives in numerous ways. This study examines the impact of changes in cancer care on patient's health-related quality of life (HRQL), which is a key outcome in cancer care. The study aims to estimate patients' self-reported HRQL before and during the pandemic and identify predictive factors for their physical and mental wellbeing.The study employed the large-scale Outpatient Cancer Care (OCC) Patient Experience Survey, including the Veterans RAND 12-Item Health Survey, to evaluate cancer patients' experiences and HRQL before (January to May 2020) and during the COVID-19 pandemic (May to July 2021). Paired t-tests were conducted to compare differences in Physical Component Scores (PCS) and Mental Component Scores (MCS) before and during the pandemic. Multivariable linear regressions were employed to investigate the factors (sociodemographic, clinical, and patient-reported experience) influencing PCS and MCS during the pandemic.PCS decreased significantly during the pandemic, while MCS remained stable. Lower PCS contributors included older age, more telehealth visits, self-reported hospitalization, and a longer time since the last cancer diagnosis. Higher PCS was associated with urban residence, higher MCS during the pandemic, and perceived active Healthcare Provider (HCP) involvement. For MCS, lower scores related to female gender and more telehealth visits, while higher scores were associated with being white, higher education, high MCS before the pandemic, and perceived active HCP involvement.The OCC Patient Experience Survey provides a unique patient level data set measuring HRQL pre- and post- the onset of the COVID-19 pandemic. The study highlights challenges faced by cancer patients during the pandemic, with a significant reduction in PCS. However, the stability in MCS suggests effective coping mechanisms. Sociodemographic, clinical, and telehealth-related variables play a complex role in shaping both PCS and MCS. Perceived HCP involvement emerges as a crucial factor correlating with higher PCS and MCS. Navigating the post-pandemic era necessitates interventions fortifying patient-provider relationships, optimizing healthcare support systems, such as telehealth services, and prioritizing mental-well-being given its impact on both PCS and MCS.© 2024. The Author(s).