急性阑尾炎是老年人的常见病。探索合适的麻醉方法对于促进老年患者术后康复至关重要。因此，本研究旨在探讨椎管内麻醉对老年阑尾炎患者的临床效果。本研究纳入2022年1月至1月在天津大学天津医院接受腹腔镜阑尾切除术（LA）的217例老年急性阑尾炎患者的临床资料。 2023年，排除8例不符合纳入标准的患者后，对209例患者的数据进行回顾性分析。根据麻醉方法的不同，研究参与者被分为参考组（n = 106）和研究组（n = 103）。比较心率（HR）、呼吸频率（RR）、收缩压（SBP）、舒张压（DBP）、血氧饱和度（SaO2）、手术时间、住院费用、出院时间、术后不良反应、炎症反应等。比较两个实验组的因子水平、视觉模拟量表（VAS）评分、肠道蠕动恢复时间、肛门排气时间、下床时间以及术后并发症发生率。我们观察到研究组的HR水平较高、RR、SBP、DBP 和 SaO2 与参考组相比 (p < 0.001)。然而，两组之间的手术时间没有差异（p > 0.05）。与参考组相比，研究组的住院费用较低，出院时间较短（p < 0.001）。同样，研究组术后不良反应发生率低于参考组（p < 0.05）。两组患者术前、术后C反应蛋白、白细胞介素6、肿瘤坏死因子-α水平比较，差异无统计学意义（p>0.05）。此外，与参考组相比，研究组在术后 3 小时、6 小时和 12 小时的 VAS 评分较低（p < 0.001）。研究组的肠道蠕动恢复时间、肛门排气时间和下床时间均显着短于参考组（p < 0.001）。另外，术后1年内两组术后并发症发生率无差异（p < 0.001）。椎管内麻醉作为一种安全的麻醉方法，可以减少接受LA的老年急性阑尾炎患者的出院时间，减少不良反应的发生，有利于术后恢复。

Acute appendicitis is a common disease in the elderly. Exploring a suitable anesthesia method is crucial in promoting postoperative recovery in elderly patients. Therefore, this study aimed to investigate the clinical effect of intraspinal anesthesia in elderly patients with appendicitis.This study included the clinical data of 217 elderly patients with acute appendicitis who underwent laparoscopic appendectomy (LA) at Tianjin Hospital of Tianjin University from January 2022 to January 2023. After excluding 8 patients who did not meet the inclusion criteria, the data from 209 patients were retrospectively analyzed. Based on the different anesthesia methods, the study participants were divided into a reference group (n = 106) and a study group (n = 103). We compared the heart rate (HR), respiratory rate (RR), systolic blood pressure (SBP), diastolic blood pressure (DBP), blood oxygen saturation (SaO2), operation duration, hospitalization costs, discharge time, postoperative adverse reactions, inflammatory factor levels, Visual Analogue Scale (VAS) score, recovery time of intestinal peristalsis, anal exsufflation time, out-of-bed time, and incidence of postoperative complications between the two experimental groups.We observed that the study group exhibited higher levels of HR, RR, SBP, DBP, and SaO2 compared to the reference group (p < 0.001). However, there was no difference in operation time between the two groups (p > 0.05). The study group showed lower hospitalization cost and shorter discharge time than the reference group (p < 0.001). Similarly, the study group had lower incidence of postoperative adverse reactions than reference group (p < 0.05). There were no significant differences in the levels of C-reactive protein, interleukin-6, and tumor necrosis factor-α between the two groups before and after surgery (p > 0.05). Furthermore, the study group had a lower VAS score compared to the reference group at 3 h, 6 h and 12 h after surgery (p < 0.001). The recovery time of intestinal peristalsis, anal exsufflation time, and out-of-bed time in the study group were substantially shorter than the reference group (p < 0.001). Additionally, there was no difference in the incidence of postoperative complications between the two groups within 1 year after surgery (p < 0.001).Intraspinal anesthesia, as a safe anesthesia method, can reduce the discharge time of elderly patients with acute appendicitis who underwent LA, and reduce the occurrence of adverse reactions, and is beneficial for postoperative recovery.