癌症相关的全身炎症导致促炎标志物和急性期蛋白增加。全身炎症反应的激活与结直肠癌预后较差有关。本研究旨在评估术前全身炎症标志物和炎症/营养评分系统在预测我们诊所接受结直肠癌根治性手术的患者术后早期（前30天）并发症和死亡率结果中的预后价值。设计为回顾性单臂横断面研究。在这项研究中，纳入了 300 名 18 岁以上接受开腹和腹腔镜结直肠癌手术的患者。记录患者的人口学特征、术前血象和生化值、手术特征、术后肿瘤病理和疾病分期。新辅助放化疗、全身炎症评分、改良格拉斯哥预后评分、那不勒斯预后评分和预后营养指数对首次治疗有显着影响。 30 天死亡率（p 值分别为 <0.001、0.007、<0.001、<0.001、<0.001）。结果表明，某些术前炎症和营养评分可能作为结直肠癌手术术后早期潜在不良结果的指标。

Cancer-related systemic inflammation causes the increase of proinflammatory markers and acute phase proteins. Activation of systemic inflammatory response has been linked to poorer prognosis in colorectal cancer. This study aims to evaluate the prognostic value of preoperative systemic inflammatory markers and inflammation/nutrition scoring systems in predicting the postoperative early period (first 30 days) complications and mortality outcomes of patients who underwent curative surgery for colorectal cancer in our clinic.This study was designed as a retrospective single-arm cross-sectional study. In this study, 300 patients older than 18 years of age who underwent open and laparoscopic surgery for colorectal cancer were included. Demographic characteristics of the patients, preoperative hemogram and biochemical values, operation characteristics, postoperative tumor pathologies and disease stages were recorded.Neoadjuvant chemoradiotherapy, Systemic Inflammation Score, Modified Glasgow Prognostic Score, Naples Prognostic Score and Prognostic Nutritional Index had a significant effect on the first 30-day mortality (p-values: <0.001, 0.007, <0.001, <0.001, <0.001, respectively).The results suggest that certain preoperative inflammation and nutrition scores might serve as indicators for potential early postoperative adverse outcomes in colorectal cancer surgery.