我们旨在探讨正念干预联合同质医学理念与单纯正念干预对结直肠癌术后化疗患者心理困扰的差异。 纳入2020年9月至2022年9月期间接受化疗的100例结直肠癌术后化疗患者并进行分组分为积极对照组（以解决方案为中心的护理干预；同质化医疗护理专业团队；专人负责《入院通知书》；出院后定期随访）和正念组（同质化医疗理念  浓缩液  正念干预），共50例各组根据不同的护理方法进行护理。护理后，正念组患者的身体功能、情绪功能、认知功能、社会功能均显着高于主动对照组。然而，正念组患者的总体生活和经济困难显着低于积极对照组（P<0.05）。护理结束后，正念组观察评分、描述评分、行动评分、内在体验评分、非判断评分、无反应评分均显着高于主动对照组（P < 0.05）。对接受化疗的结直肠癌患者进行干预，可以减轻患者的负面情绪，提高正念水平，提高患者的生活质量。© 2024。作者。

We aim to explore the differences of the psychological distress of postoperative chemotherapy patients with colorectal cancer between mindfulness intervention combined with homogeneous medical concepts and mindfulness intervention only.One hundred patients with colorectal cancer undergoing chemotherapy after surgery from Sep 2020 to Sep 2022 were enrolled and divided into active control group (Solution centered nursing interventions; homogenized medical and nursing professional teams; dedicated personnel responsible for "admission notices"; Regular follow-up after discharge) and mindfulness group (homogeneous medical concept + and concentrated solution + Mindfulness intervention) with 50 cases in each group according to different nursing methods.After nursing, the physical function, emotional function, cognitive function, and social function of the patients in the mindfulness group were significantly higher than those in the active control group. However, the overall life and economic difficulties of the patients in the mindfulness group were significantly lower than those in the active control group (P < 0.05). After nursing, the observation score, description score, action score, intrinsic experience score, non-judgment score and non-reaction score of the mindfulness group were significantly higher than those of the active control group (P < 0.05).The implementation of mindfulness intervention in colorectal cancer patients undergoing chemotherapy can alleviate the patients' negative emotions, improve the level of mindfulness, and improve the quality of life of patients.© 2024. The Author(s).