标准化的 IETA 标准提高了初级和中级超声放射科医生诊断恶性子宫内膜和宫内病变的准确性。
Standardized IETA criteria enhance accuracy of junior and intermediate ultrasound radiologists in diagnosing malignant endometrial and intrauterine lesions.
发表日期:2024 Sep 01
作者:
B Chen, P Wang, W He, P Yang, Z Kong, D Wang, L Huang, X Chen, Y Zheng, Q Chen, H Xu, J Qi
来源:
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
摘要:
将国际子宫内膜肿瘤分析(IETA)小组制定的子宫内膜和宫内病变超声特征的标准化描述转化为实用的评分方法,并探讨该方法的应用是否可以提高不同经验水平的超声放射科医生的诊断准确性这是一项对 855 名患有子宫内膜和/或宫内病变的患者进行的回顾性研究,这些患者被分为训练组 (n = 600) 和验证组 (n = 255)。具有不同经验水平(专家、中级和初级)的超声放射科医生通过主观评估并根据 IETA 规则评估所有病变。使用 IETA 规则,专家们在训练集中识别出恶性肿瘤的迹象,为每个指标分配分数,并在验证集中验证了评分方法。中级和初级超声放射科医生采用IETA评分方法重新评估病灶的恶性程度,并将其分类与之前主观评估的分类进行比较。以术后病理评估为参考标准,采用主观评估,专家们展示了最高水平的诊断准确性,敏感性为85.0%,特异性为94.3%,接受者操作特征曲线下面积(AUC)为0.897。应用 IETA 评分方法(包括对总分有贡献的 8 个超声特征),诊断恶性肿瘤的阈值大于等于 25 分,在训练集中实现了 84.7% 的敏感性、94.7% 的特异性和 0.9533 的 AUC,其中当由专家执行时,验证集中的表现相似。使用 IETA 评分方法,初级和中级超声放射科医生的敏感性(分别从 55.5% 提高到 74.8% 和从 70.2% 提高到 77.1%)、特异性(从 88.4% 提高到 91.5% 和从 87.4% 提高到 92.2%)、诊断恶性病变的AUC(分别为0.704至0.827和0.793至0.841)。IETA评分方法对子宫内膜和宫内恶性病变具有较高的诊断效能。这种方法弥补了初级和中级超声放射科医生经验的缺乏,将他们的诊断技能提高到接近经验丰富的高级超声放射科医生的水平。进一步的研究对于验证实施该方法的实用性并确认其临床价值至关重要。 © 2024 国际妇产科超声学会。© 2024 国际妇产科超声学会。
To transform the standardized descriptions of the ultrasound characteristics of endometrial and intrauterine lesions devised by the International Endometrial Tumor Analysis (IETA) group into a practical scoring method and to investigate whether application of this method enhances the diagnostic accuracy of ultrasound radiologists with different levels of experience in detecting malignancy compared with subjective assessment.This was a retrospective study of 855 patients with endometrial and/or intrauterine lesions, who were divided into a training (n = 600) and a validation (n = 255) set. Ultrasound radiologists with varying levels of experience (expert, intermediate and junior) evaluated all lesions by subjective assessment and according to IETA rules. Using IETA rules, the experts identified signs of malignancy in the training set, assigned scores for each indicator and validated the scoring method in the validation set. The intermediate-level and junior ultrasound radiologists reassessed the malignancy of the lesions using the IETA scoring method and compared their classifications with those made previously by subjective assessment. Postsurgical pathological evaluation was used as the reference standard.Using subjective assessment, the experts demonstrated the highest level of diagnostic accuracy, with a sensitivity of 85.0%, specificity of 94.3% and an area under the receiver-operating-characteristics curve (AUC) of 0.897. Applying the IETA scoring method (comprising eight ultrasound characteristics that contributed to the total score) with a threshold of > 25 points for the diagnosis of malignancy achieved a sensitivity of 84.7%, specificity of 94.7% and AUC of 0.9533 in the training set, with similar performance in the validation set, when performed by experts. Using the IETA scoring method, both junior and intermediate ultrasound radiologists showed improvement in sensitivity (from 55.5% to 74.8% and from 70.2% to 77.1%, respectively), specificity (from 88.4% to 91.5% and from 87.4% to 92.2%, respectively) and AUC (from 0.704 to 0.827 and from 0.793 to 0.841, respectively) for diagnosing malignant lesions.The IETA scoring method exhibits high diagnostic efficacy for malignant endometrial and intrauterine lesions. This method compensates for the lack of experience among junior and intermediate-level ultrasound radiologists, enhancing their diagnostic skill to a level nearing that of experienced senior ultrasound radiologists. Further research is essential to validate the practicality of implementing this method and to confirm its clinical value. © 2024 International Society of Ultrasound in Obstetrics and Gynecology.© 2024 International Society of Ultrasound in Obstetrics and Gynecology.