在这里，我们回顾了在淋巴和骨髓肿瘤的血液病理学诊断中使用的分子技术的“内容和方式”。请记住，分子检测所需的资源并非普遍可用，我们不仅将讨论能够对淋巴和骨髓肿瘤进行更高通量和复杂分析的新颖和新兴技术，还将讨论更经典、低成本的替代方法和甚至分子测试方法的一些解决方法。在这篇综述中，我们还讨论了血液病理学诊断分子技术的其他关键方面，包括预分析、数据解释和数据管理、生物信息学以及实验室间精度和性能评估。© 2024 作者。组织病理学由约翰·威利出版

Here we review the 'what and how' of molecular techniques used in the context of haematopathological diagnostics of both lymphoid and myeloid neoplasms. Keeping in mind that the required resources for molecular testing are not universally available, we will not only discuss novel and emerging techniques that allow more high-throughput and sophisticated analyses of lymphoid and myeloid neoplasms, but also the more classical, low-cost alternatives and even some workarounds for molecular testing approaches. In this review we also address other key aspects around molecular techniques for haematopatholgy diagnostics, including preanalytics, data interpretation, and data management, bioinformatics, and interlaboratory precision and performance evaluation.© 2024 The Author(s). Histopathology published by John Wiley & Sons Ltd.