本随机对照研究旨在探讨基于微信的认知行为压力管理（WB-CBSM）对接受手术切除的早期宫颈癌患者心理健康的影响。共纳入 184 名早期宫颈癌患者。癌症患者被随机分为接受 WB-CBSM (n = 92) 或正常护理 (NC) (n = 92) 8 周。与 NC 组相比，WB-CBSM 组的医院焦虑和抑郁量表 (HADS) 降低-第(M)1个月(t = 2.022，P = 0.045)、M3(t = 2.575，P = 0.011)和M6(t = 2.709，P = 0.007)的焦虑评分； M3 (χ2 = 4.834, P = 0.028) 和 M6 (χ2 = 5.182, P = 0.023) 的焦虑率； M3 (t = 2.069, P = 0.040) 和 M6 (t = 2.449, P = 0.015) 时的 HADS 抑郁评分；和 M6 时的抑郁率（χ2 = 4.268，P = 0.039）。此外，WB-CBSM组在M1（t = -2.001，P = 0.047）、M3（t = -2.281，P = 0.024）和M6（t = -2.001，P = 0.047）和M6（ t = -3.501, P = 0.001); M3（t = -2.034，P = 0.043）和M6（t = -2.426，P = 0.016）的生活质量问卷核心30（QLQ-C30）全球健康评分；以及 M3 处的 QLQ-C30 功能评分（t = -2.009，P = 0.046）。然而，各组在 M3 (t = 2.056，P = 0.041) 和 M6 ((t = 2.242，P = 0.026) 时表现出 EuroQol-5 维度评分下降，在 M1 时表现出 QLQ-C30 症状评分 (t = 2.026，P = 0.044) ）和M3（t = 2.210，P = 0.028）。WB-CBSM减少了接受手术切除的早期宫颈癌患者的焦虑和抑郁，改善了精神健康和生活质量。

This randomised controlled study was aimed at investigating the effects of WeChat-based cognitive behavioural stress management (WB-CBSM) on the mental health of patients with early-stage cervical cancer treated with surgical resection.A total of 184 patients with early-stage cervical cancer were randomised to receive either WB-CBSM (n = 92) or normal care (NC) (n = 92) for 8 weeks.Compared with the NC group, the WB-CBSM group exhibited reduced Hospital Anxiety and Depression Scale (HADS)-anxiety scores at months (M)1 (t = 2.022, P = 0.045), M3 (t = 2.575, P = 0.011), and M6 (t = 2.709, P = 0.007); anxiety rates at M3 (χ2 = 4.834, P = 0.028) and M6 (χ2 = 5.182, P = 0.023); HADS-depression scores at M3 (t = 2.069, P = 0.040) and M6 (t = 2.449, P = 0.015); and depression rates at M6 (χ2 = 4.268, P = 0.039). Moreover, the WB-CBSM group showed increased Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being scale scores at M1 (t = -2.001, P = 0.047), M3 (t = -2.281, P = 0.024), and M6 (t = -3.501, P = 0.001); the Quality of Life Questionnaire-Core 30 (QLQ-C30) global health score at M3 (t = -2.034, P = 0.043) and M6 (t = -2.426, P = 0.016); and QLQ-C30 function score at M3 (t = -2.009, P = 0.046). However, the groups exhibited decreased EuroQol-5 dimension scores at M3 (t = 2.056, P = 0.041) and M6 ((t = 2.242, P = 0.026) and QLQ-C30 symptom scores at M1 (t = 2.026, P = 0.044) and M3 (t = 2.210, P = 0.028).WB-CBSM reduced anxiety and depression and improved the spiritual well-being and quality of life of patients with early-stage cervical cancer treated with surgical resection.