许多被诊断患有肺癌的人都承受着巨大的痛苦，采取更有效的措施来帮助这些患者减轻痛苦至关重要。本研究利用荟萃分析来评估针灸联合阿片类药物治疗患者肺癌相关疼痛的安全性和有效性。我们检索了 8 个电子数据库：The Cochrane Library、PubMed、Embase、Web of Science、China National知识基础设施、中国科技期刊数据库、万方数据库、SinoMed。我们纳入了针灸联合阿片类药物治疗成人肺癌相关疼痛的所有随机对照试验。我们观察了主要结果指标，包括疼痛缓解率、数字评定量表得分和不良事件。两名研究者独立进行文献筛选、文献数据提取、文献质量偏倚风险评估。任何分歧均通过两名研究人员之间的讨论或与第三名研究人员的协商来解决。使用修订后的偏倚风险评估工具评估纳入研究的偏倚风险。使用建议、评估、制定和评价分级来评估每个结果的证据的总体质量。我们从 11 项试验中检索了 812 名肺癌患者。研究表明，与单独使用阿片类药物相比，针灸与阿片类药物联合使用可显着降低数字评定量表分数，提高疼痛缓解率，并减少副作用的发生。目前的证据表明，针灸与阿片类镇痛药相结合优于使用阿片类药物单独使用镇痛药来治疗肺癌相关疼痛。此外，这种联合疗法的不良反应较少。版权所有 © 2024 作者。由 Wolters Kluwer Health, Inc. 出版

Many individuals diagnosed with lung cancer suffer from tremendous pain, and it is crucial to implement more effective measures to assist these patients in alleviating their pain. The present study utilizes a meta-analysis to evaluate the safety and efficacy of acupuncture combined with opioids for treating lung cancer-related pain in patients.We have searched 8 electronic databases: The Cochrane Library, PubMed, Embase, Web of Science, China National Knowledge Infrastructure, China Science and Technology Journal Database, Wanfang Database, and SinoMed. We included all randomized controlled trials of acupuncture combined with opioids for lung cancer-related pain in adults. We observed the main outcome indicators, including pain relief rates, numeric rating scale scores, and adverse events. Two researchers independently conducted literature screening, literature data extraction, and assessment of bias risk in the literature quality. Any disagreements were resolved through discussions between the 2 researchers or consultations with a third researcher. The risk of bias in the included studies was assessed using the revised risk of bias assessment tool. The overall quality of evidence for each outcome was evaluated using Grading of Recommendations, Assessment, Development and Evaluations.We retrieved 812 lung cancer patients from 11 trials. The study showed that compared to opioids alone, the combination of acupuncture and opioids significantly reduced numeric rating scale scores, increased pain relief rates, and decreased the occurrence of side effects.The current evidence indicates that combining acupuncture with opioid analgesics is superior to using opioid analgesics alone for managing lung cancer-related pain. Additionally, this combination therapy has fewer adverse reactions.Copyright © 2024 the Author(s). Published by Wolters Kluwer Health, Inc.