综述肿瘤引起的大节段股骨近端骨缺损的修复重建方法，探讨其临床应用效果、优缺点及未来研究方向。肿瘤引起的股骨近端骨缺损修复重建相关的临床研究文献。根据保髋重建和非保髋重建两种主要策略对研究进行分类和分析。在保髋重建中，传统方法如同种异体移植和带血管的自体移植比较常见，但存在骨整合不良和骨整合不良的风险。骨吸收。灭活瘤段再植入和牵张成骨技术的临床应用有限。近年来，三维打印技术日趋成熟，个性化假肢、精准手术成为发展趋势。非保髋重建主要包括同种异体复合假体和全股骨置换。前者侧重于提高同种异体移植物的成活率和骨整合效率，后者则需要同时重建髋关节和膝关节的稳定性。肿瘤引起的股骨近端骨缺损的修复和重建已取得显着进展，但面临诸多挑战保持。三维打印技术与数字设计的集成为精确骨缺损修复提供了潜力。未来的努力应集中在新概念、技术和材料上，通过多学科方法提供个性化、精准的解决方案，从而提高患者的生活质量。

To review the repair and reconstruction methods for large segmental femoral proximal bone defects caused by tumors, and to explore their clinical application effects, advantages, and disadvantages, and future research directions.A comprehensive search of Chinese and foreign databases was conducted to select basic and clinical research literature related to the repair and reconstruction of femoral proximal bone defects caused by tumors. The studies were classified and analyzed based on two main strategies: hip-preserving reconstruction and non-hip-preserving reconstruction.In hip-preserving reconstruction, traditional methods such as allograft transplantation and vascularized autograft transplantation are common but have risks of poor bone integration and bone resorption. The clinical application of inactivated tumor segment reimplantation and distraction osteogenesis techniques is limited. In recent years, three-dimensional printing technology has become increasingly mature, with personalized prostheses and precise surgeries becoming development trends. Non-hip-preserving reconstruction primarily includes allograft prosthesis composite and total femoral replacement. The former focuses on improving the survival rate and bone integration efficiency of the allograft, while the latter requires the simultaneous reconstruction of hip and knee joint stability.Significant progress has been made in repairing and reconstructing proximal femoral bone defects caused by tumors, but many challenges remain. The integration of three-dimensional printing technology and digital design offers potential for precise bone defect repair. Future efforts should focus on new concepts, technologies, and materials through multidisciplinary approaches to provide personalized and precise solutions, thereby improving patient quality of life.