海鳖属是海洋绿色大型藻类中最重要的属之一，分布广泛全球，并具有高度多样性的物种和特征。这个属在海洋生态系统中扮演着重要的生态角色，是初级生产者。然而，海鳖属中的一些物种是入侵物种，可能干扰生态系统的功能。在经济上，海鳖属具有多种营养和药理成分的潜在来源。海鳖可食用，营养价值高，富含生物活性物质。因此，海鳖的某些物种已被某些亚洲国家作为食物和草药使用。近几十年来，对海鳖属的生物活性和药理性质进行的研究已经引起了科学家的关注。本次综述旨在通过评估发表的研究文章，确定过去三十年对海鳖属研究的空白，分析了其生物活性和药理性质。从海鳖中获得的化合物已经表现出明显的生物活性，如免疫刺激、抗凝血、抗癌、抗炎、抗氧化、抗病毒、抗菌、抗真菌、抗肿瘤、抗血管生成、骨保护和抗肥胖活性。本次综述提供了有关可持续利用海鳖属的指导方针的信息。 © 作者，独家授权Springer Nature B.V. 2022，Springer Nature或其许可方在作者或其他权利人的出版协议下独家拥有本文的独家权利；作者自行存档本文的已接受的手稿版本仅受此类出版协议和适用的法律规定的约束。

The genus Codium is one of the most important genera of marine green macroalgae. Its distribution is widespread worldwide and it has a high degree of diversity in species and characteristics. This genus plays an important ecological role in marine ecosystems as it is a primary producer. However, some species in the genus Codium are invasive species and may disturb the functioning of the ecosystem. Economically, Codium has promising potential as a source of diverse nutritional and pharmacological compounds. Codium is edible, has a high nutrient value, and is rich in bioactive compounds. Hence, some species of Codium have been consumed as food and used as herbal medicines in some Asian countries. In recent decades, studies of the bioactivity and pharmacological properties of the genus Codium have attracted the attention of scientists. This review aims to identify gaps in studies analyzing Codium that have been conducted in the past three decades by assessing published research articles on its bioactivity and pharmacological properties. Compounds obtained from Codium have demonstrated significant biological activities, such as immunostimulatory, anticoagulant, anticancer, anti-inflammatory, antioxidant, antiviral, antibacterial, antifungal, antitumor, anti-angiogenic, osteoprotective, and anti-obesity activities. This review provides information that can be used as a future guideline for sustainably utilizing the genus Codium.© The Author(s), under exclusive licence to Springer Nature B.V. 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.