妇女乳腺癌患者和非患者盆底功能障碍的发生和影响:横断面研究。
Occurrence and impact of pelvic floor dysfunction in women with and without breast cancer: a cross-sectional study.
发表日期:2022
作者:
Udari N Colombage, Sze-Ee Soh, Kuan-Yin Lin, Michelle White, Amanda Vincent, Jane Fox, Helena C Frawley
来源:
Brazilian Journal of Physical Therapy
摘要:
乳腺癌治疗的后遗症之一可能是骨盆底(PF)功能障碍,例如尿失禁(UI)、排便失禁(FI)和盆器官脱垂(POP)。本研究旨在比较患有和未患乳腺癌的女性之间PF功能障碍的发生率、相关困扰和影响。本横断面研究中,乳腺癌患者和非乳腺癌患者参与了调查。使用骨盆底困扰指数和骨盆底影响问卷量化PF功能障碍的发生率以及相关困扰和影响。在控制PF功能障碍已知风险因素(年龄、身体质量指数和产次)的情况下,使用逻辑和线性回归分析影响PF结果的因素。共有120名乳腺癌患者和170名无乳腺癌的女性参与。与无乳腺癌的女性相比,患有乳腺癌的女性任何类型的UI的发生率更高(百分比差=17%;95%CI:7,29)。与没有乳腺癌的女性相比,患有乳腺癌的女性经历了更高的尿路症状影响(平均差异=18.2;95%CI:8.9,27.7)。多元分析表明,患有乳腺癌(β 0.33;95%CI:0.08,0.51)是更大的尿路症状影响的最强预测因素。与未患乳腺癌的女性相比,患有乳腺癌的女性报告了更高的尿路症状发生率和影响。虽然需要进一步研究以确认我们的发现,但对于乳腺癌患者,常规筛查和提供尿路症状治疗可能是必要的。版权所有©2022 Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia。Elsevier España, S.L.U.保留所有权利。
One of the sequalae of breast cancer treatments may be pelvic floor (PF) dysfunction such as urinary incontinence (UI), faecal incontinence (FI), and pelvic organ prolapse (POP).The aim of this study was to compare the occurrence and related distress and impact of PF dysfunction between women with and without breast cancer.Women with and without breast cancer participated in this cross-sectional study. The Pelvic Floor Distress Inventory and Pelvic Floor Impact Questionnaire were used to quantify the prevalence and related distress, and impact of PF dysfunction. Factors associated with PF outcomes were examined using logistic and linear regressions while controlling for known risk factors for PF dysfunction (age, body mass index, and parity).120 women with breast cancer, and 170 women without breast cancer responded. The occurrence of any type of UI was higher in women with breast cancer than women without breast cancer (percentage difference=17%; 95% CI: 7, 29). Women with breast cancer experienced higher impact of urinary symptoms (mean difference=18.2; 95% CI: 8.9, 27.7) compared to those without. Multivariable analysis indicated that having breast cancer (β 0.33; 95%CI: 0.08, 0.51) was the strongest predictor of greater impact of urinary symptoms.Women with breast cancer reported a higher occurrence and impact of urinary symptoms than women without breast cancer. While further studies are required to confirm our findings, routine screening and offering treatment for urinary symptoms may be indicated for women with breast cancer.Copyright © 2022 Associação Brasileira de Pesquisa e Pós-Graduação em Fisioterapia. Publicado por Elsevier España, S.L.U. All rights reserved.