家用清洁产品的使用可能会导致接触到潜在有害的挥发性有机化合物（VOCs和SVOCs）。"绿色"清洁产品日益普及，但并没有官方的"绿色"标准，消费者很难知道在清洁时可能接触到的化学物质。我们测量了传统和"绿色"清洁产品释放的46种有关VOCs和SVOCs的空气浓度，在真实家庭清洁和控制室环境下进行研究，并针对可能增加女性患乳腺癌的化学物质，包括潜在的致癌物质、生殖/发育毒物或内分泌干扰物。空气样品使用气相色谱质谱和高效液相色谱进行分析。首先，在一项研究中，我们观察了50位女性使用传统或"绿色"清洁产品清洁家居时使用的产品，并采集了呼吸区域的空气样品，以确定特定产品或产品类型是否与特定VOCs和SVOCs的浓度增加相关。结果显示，使用传统漂白剂产品、消毒湿巾和洗碗液的女性呼吸区域的空气中含有多种VOCs，包括氯仿、四氯化碳、六醛和1,4-二噁烷，比没有使用这些产品的女性高。虽然与少量的"绿色"产品有关，但使用"绿色"多用途清洁剂与一些有关香料化学品的空气浓度增加相关。在实验室中，我们选择了50位女性在家中使用的9种常见传统产品和7种"绿色"产品，使用连续搅拌式流通室测量相同的VOCs。我们发现75%的最高VOC排放量来自传统清洁产品，但我们也发现了"绿色"产品的一些排放有关关注的VOCs。这种冠状病毒排放在室内的结果基本上与现实清洁的建模关联一致。 © 2022 John Wiley＆Sons A / S。发表于John Wiley＆Sons Ltd。

The use of household cleaning products can result in exposure to potentially hazardous volatile and semi-volatile organic compounds (VOCs and SVOCs). "Green" cleaning products have become increasingly available, but there is no official "green" standard, and it is difficult for consumers to know what chemicals they may be exposed to while cleaning. We measured air concentrations of 46 VOCs and SVOCs of concern released from conventional and "green" cleaning products during both real-world household cleaning and a controlled chamber environment, with a focus on chemicals that might increase women's risk of breast cancer, including possible carcinogens, reproductive/developmental toxicants, or endocrine disruptors. Air samples were analyzed using gas chromatography-mass spectrometry and high-performance liquid chromatography. First, in a study of 50 women cleaning their own homes using either conventional or "green" cleaning products, we recorded the products used and collected air samples from the breathing zone to determine whether specific products or types of products were associated with increased concentrations of specific VOCs and SVOCs. The results showed that women who used conventional bleach products, disinfecting wipes, and dish soap had higher breathing zone air concentrations of several VOCs, including chloroform, carbon tetrachloride, hexaldahyde, and 1,4-dioxane, than women who did not use these products. While fewer "green" products were associated with increases in VOC air concentrations, use of "green" all-purpose cleaners was associated with increases in air concentrations of some fragrance chemicals of concern. In the laboratory, we then selected 9 of the most common conventional products and 7 "green" products used in the in-home study for measurement of the same VOCs using a continuous stirred cylindrical flow-through chamber. We found that 75% of the highest VOC emissions were emitted by conventional cleaning products, but we also identified VOC emissions of concern from green products. VOC emissions in the chamber largely agreed with the modeled associations from real-world cleaning.© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.