动物对于癌症气味的探测能力。
Ability of animals to detect cancer odors.
发表日期：2023 Jan
作者：
Flora Gouzerh, Guila Ganem, Anaïs Pichevin, Laurent Dormont, Frédéric Thomas
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
摘要：
动物的嗅觉能力长期以来被人类用来帮助各种活动，例如狩猎、侦测地雷、搜寻人员和诊断疾病。癌症是全球导致死亡的主要疾病之一。最近的几项研究强调使用气味检测癌症的益处，本文将回顾利用动物检测肿瘤气味的研究。大量的动物被用于此目的-狗、啮齿动物、昆虫和线虫，并显示出了近乎90%的成功率来检测癌症。在这里，我们讨论这些研究、它们的方法以及所使用的动物模型。最后，我们讨论利用气味诊断癌症的医学视角。版权所有©2022 Elsevier B.V.
The olfactory capacity of animals has long been used by humans to help with various activities, e.g., hunting, detecting mines, locating people, and diagnosing diseases. Cancer is among the leading diseases causing death worldwide. Several recent studies have underscored the benefit of using scent to detect cancer, and this paper will review the studies using animals to detect tumor scents. A large variety of animals have been used for this purpose-dogs, rodents, insects, and nematodes-and have shown their capacity to detect cancer, with a success rate close to 90%. Here we discuss these studies, their methodologies, and the animal models used. Finally, we discuss the medical perspectives for cancer diagnosis using odors.Copyright © 2022 Elsevier B.V. All rights reserved.