这项研究旨在比较肌筋膜释放（MFR）对因乳腺癌引起的淋巴水肿（BCRL）患者上肢体积的影响。随机、单盲、交叉、对照试验。门诊康复临床设置。30名BCRL患者。在交叉设计中，随机分配治疗顺序，15名受试者接受4周的MFR治疗，随后为期4周的洗脱期，然后接受安慰剂MFR，另外15名受试者以相反的顺序接受干预。每个治疗过程持续60分钟，包括30分钟的MFR或安慰剂MFR，然后每周两次进行完全减压疗法约30分钟。主要结果为上肢体积，次要结果为主观疼痛、肩关节活动度（ROM）、胸部活动度、肩部功能和生活质量，在每次干预期间的开始和结束前进行评估。 MFR和安慰剂MFR都有明显的上肢体积差异（P <0.05），但两种治疗方法之间没有显著差异（P>0.05）。MFR治疗也比安慰剂MFR治疗在主观疼痛和肩ROM方面获得更大的改善（P <0.05），但在内转方面和肩部功能方面没有显著差异。 基于MFR的治疗通过减少水肿体积和疼痛，改善了ROM和胸部活动度，从而在肩部功能方面实现了临床改善，进一步进行平行随机对照试验的研究可以确认本研究的结果。基于MFR的治疗被认为是BCRL康复的重要组成部分。此外，基于MFR的治疗可能对BCRL患者是安全的。

This study aimed to compare the effects of myofascial release (MFR) on upper extremity volume in patients with breast cancer-related lymphedema (BCRL).A randomized, single-blinded, cross-over, controlled trial.An outpatient rehabilitation clinical setting.Thirty patients with BCRL.Within a crossover design with randomized treatment sequences, fifteen subjects received MFR for 4 weeks, followed by 4 weeks of washout period, and then received placebo MFR and the other fifteen subjects received interventions in the reverse order. Each session had a 60 min process including either MFR or placebo MFR for 30 min, followed by complete decongestive therapy for 30 min twice a week. Upper limb volume as the primary outcome and subjective pain, shoulder range of motion (ROM), chest mobility, shoulder function, and quality of life as secondary outcomes were assessed before and at the end of each intervention period.There were significant differences in upper limb volume after both MFR and placebo MFR (P<0.05) while no significant difference between MFR and placebo MFR treatments was found (P>0.05). MFR-based treatment also achieved a greater improvement than placebo MFR-based treatment in subjective pain and shoulder ROM (P<0.05), except for internal rotation, and shoulder function.MFR-based treatment showed clinical improvement in shoulder function, induced by decreased edema volume and pain, and improved ROM and chest mobility. However, a further study with parallel randomized controlled trials to confirm what was achieved in the present study.MFR-based treatment is considered an important part of BCRL rehabilitation. Moreover, MFR-based treatment may be safe for patients with BCRL.