宫颈癌是女性中最常见的恶性肿瘤，由长期不治的特定人乳头瘤病毒（HPV）基因型感染引起。它是全球女性第四大常见癌症。两种致癌基因型，HPV16和18负责全球超过70％的宫颈癌。如果早期检测得到，宫颈癌是一种最容易预防和治疗的癌症之一。在本综述文章中，我们总结了临床诊断和研究实验室中用于检测与宫颈癌相关的HPV变化的不同方法，以更好地了解这些测试的优点和局限性。尽管宫颈癌筛查策略已被广泛认知，但由于各种因素，发展中国家缺乏有效实施。随着宫颈癌病例的当前增长速度，精确和及时地识别HPV可显著影响宫颈癌的预防和有效管理。宫颈癌是发展中国家最常见的妇科癌症。细胞学和HPV分子检测的主要筛查测试对于预防宫颈癌非常重要。为了解决这些问题，已经开发了几种现场检测试剂盒，以方便快速筛查HPV并获得最少的周转时间。

Cervical cancer is the most frequent malignancy among women caused by an unresolved long-term infection with distinct human papillomavirus (HPV) genotypes. It is the fourth most common form of cancer among women worldwide. The two oncogenic genotypes, HPV 16 and 18, are responsible for >70% of all cervical cancers worldwide. Cervical cancer is one of the most successfully preventable and treatable forms of cancer if detected early.In this review article, we have summarizedsummarised the different approaches used in clinical diagnosis and research laboratories to detect HPV-related changes associated with cervical cancer for a better understanding of the advantages and limitations of these tests.Despite the well-known screening strategies for cervical cancer, developing nations lack effective implementation due to various factors. With the current rate of cervical cancer cases, precise and timely identification of HPV can significantly impact the prevention and efficient management of cervical cancer. Cervical cancer is the most common gynecological cancer in developing countries. The primary screening test with cytology and molecular testing of HPV is important for preventing cervical cancer. To address these issues, several point-of-care assays have been developed to facilitate rapid screening of HPV with the least turnaround time.