在1999年至2018年期间，描述子宫颈癌的发病率和生存结果。韩国中央癌症登记处确定了1999年至2018年诊断为宫颈癌的患者。计算年龄标准化发病率（ASR）和年百分比变化（APC）。分析组织学、诊断年份（1999-2008年vs.2009-2018年）、分期和诊断年龄的生存率。20年间宫颈癌的绝对发病率从1999年的4,488降至2018年的3,500，APC为-3.42%（p <0.0001）。鳞状细胞癌（SCCA）的ASR从1999年的每10万人中13.27个减少到2018年的6.16个（APC为-4.04%），而腺癌则在增加（ASR每10万人从1.30个至1.92个，APC为1.52%<0.0001）。腺癌患者的年龄比SCCA患者年轻（均值为49.9±12.7岁和52.9±14.6岁；p<0.0001）。总的宫颈癌患者的五年生存率为78.0%。腺癌的生存率比SCCA差（5年生存率分别为76.8%和79.8%；p<0.0001）。在1999-2008年和2009-2018年之间诊断的患者生存没有差异。早期癌症生存率更好（局部、区域和远端疾病的五年生存率分别为90.0%，69.9%和26.5%；p<0.0001）。年龄小于50岁的患者比50岁及以上的患者生存率更好（分别为87.1%和69.8%；p<0.0001）。 1999年至2018年，宫颈鳞状细胞癌发病率下降，而腺癌在韩国缓慢但显着增加。腺癌的诊断年龄比SCCA低，但生存结果更差。© 2023年。亚洲妇科肿瘤学会、韩国妇科肿瘤学会和日本妇科肿瘤学会。

To describe the incidence and survival outcomes of uterine cervical cancer during 1999-2018.Patients who were diagnosed with cervical cancer during 1999-2018 were identified in the Korea Central Cancer Registry. Age-standardized incidence rates (ASRs) and annual percent changes (APCs) were calculated. Survival rates by histology, year of diagnosis (1999-2008 vs. 2009-2018), stage, and age at diagnosis were analyzed.The absolute incidence of cervical cancer decreased over 20 years from 4,488 in 1999 to 3,500 in 2018, with an APC of -3.42% (p<0.0001). While ASR of squamous cell carcinoma (SCCA) more than halved from 13.27 per 100,000 in 1999 to 6.16 in 2018 (APC, -4.04%), adenocarcinoma continued to rise (ASR, 1.30 per 100,000 to 1.92; APC, 1.52%; p<0.0001). Patients with adenocarcinoma were younger than those with SCCA (mean, 49.9±12.7 vs. 52.9 ±14.6 years; p<0.0001). Five-year survival rate of cervical cancer patients overall was 78.0%. Adenocarcinoma had poorer survival than SCCA (5-year survival rate, 76.8% vs. 79.8%; p<0.0001). There was no survival difference between patients who were diagnosed between 1999-2008 and 2009-2018. Earlier-stage disease had better survival (5-year survival rate for localized, regional, and distant disease, 90.0% vs. 69.9% vs. 26.5%; p<0.0001). Younger patients aged <50 years had better survival than those aged ≥50 years (87.1% vs. 69.8%; p<0.0001).The incidence of SCCA of the uterine cervix declined while adenocarcinoma continued to increase slowly but significantly from 1999 to 2018 in Korea. Adenocarcinoma was diagnosed at a younger age, but had poorer survival outcome than SCCA.© 2023. Asian Society of Gynecologic Oncology, Korean Society of Gynecologic Oncology, and Japan Society of Gynecologic Oncology.