评估和比较不同运动类型在减轻接受化疗的癌症患者的癌症相关疲劳（CRF）方面的有效性。还比较了所选运动类型的运动强度。我们在MEDLINE、Embase、CINAHL、Scopus、SPORTDiscus和Web of Science中进行了检索，时间从开始到2021年10月15日。包括关于运动方式对接受化疗的癌症患者的CRF有效性的随机对照试验。使用结构化协议提取研究特征。评估方法质量采用PEDro评分和修订后的Cochrane随机试验偏倚工具进行评估。基于推荐、评估、开发和评估的分类评估证据的确定性。使用调整后的标准化平均差（SMD）或Hedge's g作为效应度量，同时带有相应的95％置信区间（CI）。共包括47个研究。使用随机效应模型进行数据汇总。添加低强度有氧和抗阻性运动（SMD=1.28，95% CI -0.18；2.75，P = .086），或中等强度有氧和抗阻性运动（SMD=0.85；95% CI -0.12；1.82，P = .087）的趋势比添加柔韧性训练到常规护理更为有效。UC单独比添加中等强度有氧和抗阻性运动到UC（SMD = -0.47，95％ CI -0.96，0.02，P = .060）中更有效。添加低至中等强度的有氧和/或抗阻性运动表现出对比UC单独或UC加柔韧性训练有改善CRF的积极趋势。版权所有©2023年该作者。Elsevier Inc.发表。保留所有权利。

To assess and compare the effectiveness of different exercise modalities in reducing cancer-related fatigue (CRF) in patients with cancer undergoing chemotherapy. Exercise intensities for selected exercise types were also compared.We conducted a search in MEDLINE, Embase, CINAHL, Scopus, SPORTDiscus, and Web of Science from inception to October 15, 2021.Randomized controlled trials concerning the effectiveness of exercise modalities on CRF in patients with cancer undergoing chemotherapy were included.Study characteristics were extracted using a structured protocol. Methodological quality was assessed employing the PEDro scale and risk of bias was assessed using the Revised Cochrane Risk of Bias Tool for Randomized Trials. The certainty of evidence was assessed based on Grading of Recommendations, Assessment, Development and Evaluation. The measure of effect used was the adjusted standardized mean difference (SMD) or Hedge's g, together with the corresponding 95% confidence intervals (CI).Forty-seven studies were included. Data were pooled employing a random-effects model. There was a trend that adding low-intensity aerobic and resistance exercise (SMD=1.28, 95% CI -0.18; 2.75, P=.086), or moderate-intensity aerobic and resistance exercise (SMD=0.85; 95% CI -0.12; 1.82, P=.087), was more effective than adding flexibility training to usual care (UC). There was also a trend that UC alone was less effective than adding moderate-intensity aerobic and resistance exercise (SMD=-0.47, 95% CI -0.96, 0.02, P=.060) to UC.The addition of low- to moderate-intensity aerobic and/or resistance exercise demonstrated a positive trend for improvement in CRF in patients with cancer undergoing chemotherapy, when compared with UC alone or UC with flexibility training.Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.