这个系统综述和荟萃分析的目的是评估早期宫颈癌和早期高或高中度风险子宫内膜癌经盆底淋巴结切除术（PLND）后淋巴囊肿和症状性淋巴囊肿的比例和风险因素。在PubMed、Embase和Cochrane图书馆进行了报告PLND后淋巴囊肿比例的研究。由两名评审员独立地按标题/摘要和全文筛选检索到的研究。使用Newcastle Ottawa量表和Cochrane偏倚风险工具进行质量评估。通过随机效应荟萃分析汇总淋巴囊肿和可能的风险因素。从检索到的233篇研究中，包括了24篇研究。淋巴囊肿的汇总比例为14％，症状性淋巴囊肿的比例为3％。例行诊断与根据需要进行的诊断相比，与淋巴囊肿的比例显着增加相关（21％与4％，p <0.01）。开腹手术方法导致淋巴囊肿的比例显着高于腹腔镜手术方法（18% vs 7%，p = 0.05）。当> 15％的研究人口进行额外的腹主动脉淋巴结切除（PAOLND）时，淋巴囊肿的比例显着增高（15% vs 3%，p <0.01）。平均淋巴结清除数量<21会导致淋巴囊肿的比例显着增高，而平均数量为21或更高时则相反（19% vs 5%，p = 0.02）。其他分析的风险因素包括BMI、淋巴结转移、辅助放疗和随访。没有足够数据检测症状性淋巴囊肿发展的显着风险因素。汇总淋巴囊肿的比例为14％，其中症状性淋巴囊肿发生率为3％。导致淋巴囊肿总比例显著的风险因素包括开腹手术方法、淋巴结清除数减少和额外PAOLND。版权所有© 2023年作者。由Elsevier Inc.发表。保留所有权利。

The purpose of this systematic review and meta-analysis was to evaluate the proportion and risk factors of lymphoceles and symptomatic lymphoceles after PLND in early-stage cervical and early-stage high or high-intermediate risk endometrial cancer.Studies reporting on the proportion of lymphocele after PLND were conducted in PubMed, Embase and Cochrane Library. Retrieved studies were screened on title/abstract and full text by two reviewers independently. Quality assessment was conducted using the Newcastle Ottowa Scale and the Cochrane risk-of-bias tool. Proportion of lymphocele and possible risk factors were pooled through random-effects meta-analyses.From the 233 studies retrieved, 24 studies were included. The pooled proportion of lymphocele was 14% and of symptomatic lymphocele was 3%. Routinely performing diagnostics was associated with a significantly higher proportion of lymphocele compared to diagnostics performed on indication (21% versus 4%, p < 0.01). Laparotomic surgical approach led to a significantly higher proportion of lymphoceles than laparoscopic surgical approach (18% versus 7%, p = 0.05). The proportion of lymphocele was significantly higher when >15% of the study population underwent additional paraaortic lymph node dissection (PAOLND) opposed to <15% (15% versus 3%, p < 0.01). A mean number of lymph nodes dissected of <21 resulted in a significantly higher pooled proportion of lymphoceles opposed to when the mean number was 21 or higher (19% versus 5%, p = 0.02). Other risk factors analysed were BMI, lymph node metastasis, adjuvant radiotherapy and follow up. There was no sufficient data to detect significant risk factors for the development of symptomatic lymphoceles.The pooled proportion of lymphocele was 14% of which symptomatic lymphoceles occurred in 3%. Significant risk factors for the total proportion of lymphoceles were laparotomic approach, decreased number of lymph nodes dissected and additional PAOLND.Copyright © 2023 The Authors. Published by Elsevier Inc. All rights reserved.