具有分散型风险的弯曲型巨型细胞肿瘤的MRI预测模型
MRI Prediction Model for Tenosynovial Giant Cell Tumor with Risk of Diffuse-type
影响因子:3.90000
分区:医学2区 / 核医学2区
发表日期:2023 Nov
作者:
Jun-Ho Kim, Seul Ki Lee, Jee-Young Kim
摘要
提出一个磁共振成像（MRI）预测模型，用于分类的型型型斜型链型巨型细胞肿瘤（D-TSGCTS）。对动态位置进行了分类，然后在MRI上评估了结节性，边缘，外周，外周和内部高压，以及骨和骨骼的参与。包括学生的t检验，卡方检验，诊断性能，逻辑回归分析和决策树。包括关节内（11个局部化；八个弥漫性）和55个外关节外（44个局部; 11个局部; 11个弥漫性）TSGCT。 Extra-articular D-TSGCTs showed significantly more frequent multinodular (72.7% vs. 25.0%, p = 0.009), and infiltrative lesions (90.9% vs. 34.1%, p = 0.002), without peripheral hypointensity (90.9% vs. 18.2%, p < 0.001), and contained granular internal hypointensity (72.7% vs. 31.8%; P = 0.003）比本地化型骨（81.8％vs. 27.3％; P = 0.003）和软骨（50.0％vs. 0.0％; P = 0.038）的参与。 Intra-articular D-TSGCT also showed significance in all MRI features (100.0% vs. 9.1%, p = 0.001; 100.0% vs. 27.3%, p = 0.007; 100.0% vs. 36.4%, p = 0.018; 100.0% vs. 27.3%, p = 0.007; 50.0% vs. 0.0%, p = 0.038), except bone involvement （37.5％比9.1％，p = 0.352）比局部类型。软骨介入显示最高特异性（88.6-100.0％），无论位置如何。结节性（100.0％;赔率[OR]：70.000）和外周高度（90.9％; OR：62.250）在分别在关节内和关节外病例中表现出对D-TSGCT的最高敏感性ORS。 D-TSGCG的MRI模型从软骨的参与开始，在解剖学位置以及下一个在关节内和关节外部的结节性和周围性低强度开始，在100％和90.9％的敏感性和90.9％的敏感性和90.9％的特异性中，对于超级和100％和77.2％的范围均可表现出来。 D-TSGCT通过将成像特征与解剖位置相结合。
Abstract
To propose a magnetic resonance imaging (MRI) prediction model for diffuse-type tenosynovial giant cell tumors (D-TSGCTs).Anatomic locations were classified and then nodularity, margin, peripheral and internal hypointensity, and bone and cartilage involvement were evaluated on MRI. Student's t-test, chi-square test, diagnostic performance, logistic regression analysis, and decision tree were performed.Nineteen intra-articular (11 localized; eight diffuse) and 55 extra-articular (44 localized; 11 diffuse) TSGCTs were included. Extra-articular D-TSGCTs showed significantly more frequent multinodular (72.7% vs. 25.0%, p = 0.009), and infiltrative lesions (90.9% vs. 34.1%, p = 0.002), without peripheral hypointensity (90.9% vs. 18.2%, p < 0.001), and contained granular internal hypointensity (72.7% vs. 31.8%; p = 0.003) with more frequent bone (81.8% vs. 27.3%; p = 0.003) and cartilage (50.0% vs. 0.0%; p = 0.038) involvement than localized-type. Intra-articular D-TSGCT also showed significance in all MRI features (100.0% vs. 9.1%, p = 0.001; 100.0% vs. 27.3%, p = 0.007; 100.0% vs. 36.4%, p = 0.018; 100.0% vs. 27.3%, p = 0.007; 50.0% vs. 0.0%, p = 0.038), except bone involvement (37.5% vs. 9.1%, p = 0.352) than localized-type. Cartilage involvement revealed the highest specificity (88.6-100.0%), regardless of location. Nodularity (100.0%; odds-ratio [OR]: 70.000) and peripheral hypointensity (90.9%; OR: 62.250) demonstrated the highest sensitivities ORs for D-TSGCT in intra-articular and extra-articular cases, respectively. MRI models for D-TSGCG beginning with the cartilage involvement in both anatomic locations and next on nodularity and peripheral hypointensity in intra-articular and extra-articular locations, respectively, exhibited sensitivity and specificity of 100% and 90.9% for intra-articular and 100% and 77.2% for extra-articular TSGCTs, respectively.MRI can suggest the risk of D-TSGCT by combining imaging features with anatomic locations.