金融毒性描述了患者在癌症治疗中由于经济和时间成本而遭受的不利影响。患者经历的经济负担来自于大量的个人支出，这通常与因病假导致的收入减少同时发生。根据用于评估的工具，大约有一半的妇科癌症患者受到经济毒性的影响。患者在三个领域体验金融毒性：影响患者物质条件的经济困难（如医疗债务）、心理反应（如痛苦）和患者采取的与健康相关的应对行为（如因费用而放弃治疗）。癌症患者的金融毒性加重与生活质量下降、建议治疗依从性下降和整体生存率更差有关。在本综述中，我们描述了有关金融毒性的当前文献研究，包括如何使用经过验证的工具进行评估、对患者的影响、风险因素以及幸存者就业方面的关注。在可能的情况下，我们重点介绍了特定于妇科癌症患者的研究数据。我们还回顾了旨在缓解金融毒性的干预研究，并向读者提供目前正在使用的干预措施的实际例子。最后，我们概述了与金融毒性相关的卫生政策发展，并倡导开展创新的策略来减少妇科癌症诊断后患者所经历的金融毒性。Copyright © 2023 Elsevier Inc. All rights reserved.

Financial toxicity describes the adverse impact patients experience from the monetary and time costs of cancer care. The financial burden patients experience comes from substantially increased out-of-pocket spending that often occurs concurrent with reduced income due to sick leave from work. Financial toxicity is common affecting approximately half of patients with a gynecological cancer depending on the validated instrument used for measurement. Financial toxicity is experienced by patients in three domains: economic hardship affecting patients' material conditions (i.e., medical debt), psychological response (i.e., distress), and health-related coping behaviors that patients adopt (i.e., foregoing care due to costs). Higher financial toxicity among cancer patients has been associated with decreased quality of life, impaired adherence to recommended care, and worse overall survival. In this review, we describe the current literature on financial toxicity, including how it can be assessed with validated tools, the downstream impact on patients, risk factors, and employment concerns of survivors. Whenever possible, we highlight data from research featuring patients with gynecologic cancer specifically. We also review studies with interventions aimed to mitigate financial toxicity and offer the reader real world examples of interventions currently being used. Lastly, we provide an overview of health policy developments relevant to financial toxicity and advocate for innovation in the development and implementation of strategies to decrease the financial toxicity patients experience following a diagnosis of gynecologic cancer.Copyright © 2023 Elsevier Inc. All rights reserved.