研究动态
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乳腺癌患者在辅助放疗之后的决策后悔。

Decision regret in breast cancer patients after adjuvant radiotherapy.

发表日期:2023 Feb 01
作者: Mümtaz Köksal, Clara Hoppe, Anna-Katharina Schröder, Davide Scafa, David Koch, Gustavo R Sarria, Christina Leitzen, Alina Abramian, Christina Kaiser, Andree Faridi, Christoph Henkenberens, Leonard C Schmeel, Frank A Giordano
来源: BREAST

摘要:

乳腺癌患者通常会进行共同决策,从多个选择中选择个性化的治疗方案。然而,治疗效果不佳可能会导致决策后悔。我们评估了进行辅助放疗的乳腺癌患者的决策后悔、身体和心理健康状况,并探讨了它们与患者、肿瘤、治疗和症状特征的关系。这项横断面研究涉及回顾性地获取临床数据和通过定期长期医疗随访进行的采访收集的数据。使用Ottawa决策后悔量表评估了放疗方面的决策后悔,使用PROMIS全球健康-10问卷评估了身体和心理健康状况,并询问了患者的治疗结果和症状。问卷调查在放疗完成后14个月至4年进行。在包括172名乳腺癌患者的研究中,只有13.9%的患者表达了高决策后悔,大多数患者表达了很少或没有决策后悔。更多的决策后悔与使用容积调制弧放疗、胸壁照射、多西他赛作为化疗药物、淋巴管癌症和放疗后新心脏病有关,与心理健康较差有关。虽然大多数患者报道很少或没有决策后悔,但我们确定了与更多决策后悔相关的几个患者、治疗和症状特征。我们的发现表明,心理健康状况影响患者对治疗决策的满意度,这意味着从业者在共同决策过程中应特别关注维护心理健康,并确保提供心理评估和治疗以处理放疗的长期影响。版权所有 © 2023 The Authors. 由Elsevier Ltd.发表。保留所有权利。
Breast cancer patients often engage in shared decision-making to select an individualized treatment regimen from multiple options. However, dissatisfaction with treatment outcomes can lead to decision regret. We evaluated decision regret and physical and psychological well-being among breast cancer patients who underwent adjuvant radiotherapy and explored their associations with patient, tumor, treatment, and symptom characteristics.This cross-sectional study involved retrospectively obtaining clinical data and data collected through interviews carried out as part of regular long-term medical aftercare. Decision regret regarding the radiotherapy was assessed using the Ottawa Decision Regret Scale, physical and psychological well-being were assessed using the PROMIS Global Health-10 questionnaire, and patients were asked about their treatment outcomes and symptoms. The questionnaire was administered 14 months to 4 years after completion of radiotherapy.Of the 172 included breast cancer patients, only 13.9% expressed high decision regret, with most patients expressing little or no decision regret. More decision regret was associated with volumetric modulated arc therapy, chest wall irradiation, use of docetaxel as a chemotherapy agent, lymphangiosis carcinomatosa, new heart disease after radiotherapy, and lower psychological well-being.Although most patients reported little or no decision regret, we identified several patient, treatment, and symptom characteristics associated with more decision regret. Our findings suggest that psychological well-being influences patients' satisfaction with therapy decisions, implying that practitioners should pay special attention to maintaining psychological well-being during shared decision-making and ensuring that psychological assessment and treatment is provided after cancer therapy to deal with long-term effects of radiotherapy.Copyright © 2023 The Authors. Published by Elsevier Ltd.. All rights reserved.