局部晚期肺癌（LALC）的放射治疗（RT）治疗可能很具挑战性。放射科医师和放射肿瘤科医师（ROs）之间的多学科合作可以优化RT计划，减少随访影像解释的不确定性，并改善结果。在这项临床治疗试验中，共有37名接受LALC 定向RT治疗的患者，6名放射肿瘤科医师和3名胸部放射科专家在四个治疗中心被纳入研究。在最终确定RT计划之前，代表性的计算机断层扫描（CT）切片，并在其上叠加初步辐照目标的轮廓，与放射科医师团队共享。主要终点是在至少50% 的计划中在RT仿真后最多4个工作日内收到反馈的可行性。共纳入37例肺癌患者，且36例RT计划得到审核。在审核的35例中，平均年龄为69岁。其中，有27个计划（73%）在4天或更短的时间内收到了反馈（四分位范围为3-4天）。35例中有13例（37％）接受反馈，指出划定的目标可能未涵盖所有可疑肿瘤受累的部位。总共，对于35例计划中的16例（46％），对于过度或不足覆盖的部位做出了建议，并在所有案例中实施。放射学评估未导致治疗延误，并且明显更改了照射体积：肿瘤总体积，-1.9至+ 96.1％；计划靶体积，-37.5至+ 116.5％。通过简化的工作流程进行跨学科协作的RT计划是可行的，可以避免治疗延误，并促使对RT靶部位进行重大改变。版权所有©2023大学放射科医师协会。由Elsevier Inc.出版。保留所有权利。

The treatment of locally advanced lung cancer (LALC) with radiotherapy (RT) can be challenging. Multidisciplinary collaboration between radiologists and radiation oncologists (ROs) may optimize RT planning, reduce uncertainty in follow-up imaging interpretation, and improve outcomes.In this prospective clinical treatment trial (clinicaltrials.gov XXX), 37 patients receiving definitive RT for LALC, six attending ROs, and three thoracic radiologists were consented and enrolled across four treatment centers. Prior to RT plan finalization, representative computed tomography (CT) slices with overlaid outlines of preliminary irradiation targets were shared with the team of radiologists. The primary endpoint was to assess feasibility of receiving feedback no later than 4 business days of RT simulation on at least 50% of plans.Thirty-seven patients with lung cancer were enrolled, and 35 of 37 RT plans were reviewed. Of the 35 patients reviewed, mean age was 69 years. For 27 of 37 plans (73%), feedback was received within 4 or fewer days (interquartile range 3-4 days). Thirteen of 35 cases (37%) received feedback that the delineated target potentially did not include all sites suspicious for tumor involvement. In total, changes to the RT plan were recommended for over- or undercoverage in 16 of 35 cases (46%) and implemented in all cases. Radiology review resulted in no treatment delays and substantial changes to irradiated volumes: gross tumor volume, -1.9 to +96.1%; planning target volume, -37.5 to +116.5%.Interdisciplinary collaborative RT planning using a simplified workflow was feasible, produced no treatment delays, and prompted substantial changes in RT targets.Copyright © 2023 The Association of University Radiologists. Published by Elsevier Inc. All rights reserved.