超声成像近期因引进一种新的70兆赫探头而获益，该探头能够提供高分辨率图像，即超高频超声成像（UHFUS）。通过 UHFUS 检查研究基底细胞癌（BCC）的形态学特征和测量 BCC 厚度。这项回顾性多中心研究包括171名连续接受 UHFUS 检查的患者，时间从2018年11月至2019年5月，以疑似 BCC 为主。诊断通过组织病理学确认。研究了一系列形态学参数，包括回声强度、结构、边界、形状和组成（即有无病变内结构），以及客观测量，如厚度（即表皮表面与肿瘤最深处之间的最大距离）和宽度。共检查了117例表浅性（n=13; 11.1%）、结节性（n=64; 54.5%）、浸润性（n=17; 14.5%）、混合型（n=18; 16.1%）和其他亚型（n=2; 1.8%）的 BCC。最常见的 UHFUS 参数包括：低回声信号（80/117，68.4%，p＜0.0001）、均质结构（76/117，65%，p=0.012）、明确界限（77/117，65.8%，p=0.0006）和细长形状（71/117，60.7%，p＜0.0001）。BCC 厚度在 UHFUS 和组织学估计值之间的相关性极高（内部类相关系数-ICC＞0.8）。UHFUS 是一种新型快速、简便、非侵入性的皮肤成像技术，能够实时提供关于 BCC 大小和形态的数据，并可在床边使用。这些特点使得 UHFUS 在预手术定位、疾病复发的检测以及治疗监测等各种可能的应用中非常有用。© The Author(s) 2023. Published by Oxford University Press on behalf of British Association of Dermatologists. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Ultrasound imaging has recently benefited from the introduction of a new 70 MHz transducer able to provide high-resolution images, i.e.: ultra-high-frequency ultrasound (UHFUS).To study the morphological features of Basal Cell Carcinoma (BCC) and measure BCC thickness by means of UHFUS examination.This retrospective multicentric study included 171 consecutive patients that underwent UHFUS examination between November 2018 and May 2019 for suspeted BCC. Diagnosis was confirmed by histopathology. A series of morphologic parameters including echogenicity, structure, borders, shape composition (i.e., presence of intralesional structures) were investigated along with objective measurements such as thickness (i.e., maximum distance between the surface of the epidermis and the deepest part of the tumor) and wideness.A total of 117 BCC of superficial (n = 13; 11.1%), nodular (n = 64; 54.5%), infiltrative (n = 17; 14.5%), mixed subtype (n = 18; 16.1%) and other subtypes (n = 2; 1.8%) were examined. The most frequently observed UHFUS parameters included: hypoechoic signal (80/117, 68.4%, p < 0.0001), homogeneous structure (76/117, 65%, p = 0.012), well-defined borders (77/117, 65.8%, p = 0.0006) and elongated shape (71/117, 60.7%, p < 0.0001). An excellent correlation was found between the BCC thickness measured by UHFUS and the value estimated by histology (interclass correlation - ICC > 0.8).UHFUS is a new rapid and easy non-invasive skin imaging technique able to provide data on the dimension and morphology of BCC in real-time and at bed-site. These characteristics makes UHFUS useful in a plethora of possible application, ranging from the pre-surgical mapping to the detection of disease recurrence to the treatment monitoring.© The Author(s) 2023. Published by Oxford University Press on behalf of British Association of Dermatologists. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.