研究动态
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藤黄果:植物化学和药理学应用。

Garcinia gummi-gutta: Phytochemicals and pharmacological applications.

发表日期:2023 Feb 13
作者: Amrita Thandayamparambil Anilkumar, Suryaa Manoharan, Satheeswaran Balasubramanian, Ekambaram Perumal
来源: BIOFACTORS

摘要:

藤黄果,又名藤黄果实,是金丝桃科的一种。藤黄果是一个有200种树木和灌木的多配偶属,分布在世界各地,包括亚洲热带地区。仅在印度就发现了约30种,它们被广泛用作调味剂,在印度南部地区,特别是在喀拉拉邦和卡纳塔克邦,用于装饰鱼咖喱。藤黄果的果皮在传统上被用于治疗胃肠问题、腹泻和溃疡。其乡土植物学性质表明南印度人民一直在传统上应用它。原果实提取物的体内和体外效应显示出抗炎、抗癌、驱虫、抗微生物和抗氧化活性。藤黄果皮具有药用价值,在阿育吠陀和传统医学中常常用于治疗多种疾病。从藤黄果中分离出的各种次生代谢产物,如有机酸羟基柠檬酸(HCA)、类黄酮、萜类、多糖和多异戊二烯苯并酮等,具有多种药理活性。本文综述了藤黄果的生物活性、植物化学和民族植物学应用。©2023国际生物化学和分子生物学联合会。
Garcinia gummi-gutta, also known as Garcinia cambogia, is a member of the Guttiferae family. Garcinia is a polygamous genus consisting 200 species of trees and shrubs. It is found in different zones of the planet including Asia's tropical regions. In India alone, around 30 species have been discovered. They are widely used as a flavoring agent to garnish fish curry in southern India, particularly in Kerala and Karnataka. The fruit rind of G. gummi-gutta has traditionally been used to treat gastrointestinal problems, diarrhea, and ulcers. South Indian people have been utilizing it traditionally as evidenced by its ethnobotanical properties. In vivo and in vitro effects of the crude fruit extract showed anti-inflammatory, anti-cancer, anthelmintic, anti-microbial, and antioxidant activities. G. gummi-gutta fruit rind is medicinally significant and is frequently used in ayurvedic and traditional medicine for many diseases. Various secondary metabolites such as organic acids-hydroxycitric acid (HCA), flavonoids, terpenes, polysaccharides and polyisoprenylated benzophenones-garcinol, xanthochymol, guttiferone, benzophenone, xanthone, biflavonoids, alkaloids, tannins, phenols, and saponins isolated from the G. gummi-gutta have diverse pharmacological activities. This review provides a summary of G. gummi-gutta, including its biological activities, phytochemistry, and ethnobotanical applications.© 2023 International Union of Biochemistry and Molecular Biology.