微创手术是一种不断扩大的手术领域，它已经取代了许多传统开放式的外科技术。尽管手术仍是食管癌治疗的基石，但它仍然存在相当严重的并发症和技术难点。介导镜辅助下的食管切除术是一种有前途的技术，旨在减轻手术负担并加强康复。本研究在PubMed、MEDLINE 和 EMBASE数 据库上搜索了关于介导镜辅助下的食管癌切除术的出版物。主要终点是手术后吻合口漏，次要终点则包括对收取的淋巴结、失血量、乳糜漏、住院时间、手术时间、肺炎、伤口感染、死亡率以及显微镜下的阳性切除端 (R1) 的评估。二进制和连续结果分别计算了汇总事件率 (PER) 和汇总平均数。在 2274 项搜索研究中，有 26 项纳入分析。综合分析结果显示，吻合口漏的汇总事件率 (PER) 为 0.145 (0.1144；0.1828)。乳糜漏、喉返神经损伤/嗓音嘶哑、术后肺炎、伤口感染、早期死亡、术后并发症和显微镜下阳性 (R1) 切缘的汇总事件率分别为 0.027、0.185、0.09、0.083、0.020、0.378 和 0.037。总失血量、住院时间、手术时间、总收获淋巴结数和胸腔淋巴结数的汇总平均数分别为 159.209、15.187、311.116、23.379 和 15.458。介导镜辅助下的食管切除术是一种有前途的微创技术，避免了胸壁切口、患者转位和肺部操作，从而使手术时间缩短、失血量减少并减少术后并发症。在癌症安全和淋巴结切除方面也可靠。© 2023。本文是美国政府工作，未受版权保护；可能适用外国版权保护。

Minimally invasive surgery is an expanding field of surgery that has replaced many open surgical techniques. Surgery remains a cornerstone in the treatment of esophageal cancer, yet it is still associated with significant morbidity and technical difficulties. Mediastinoscope-assisted esophagectomy is a promising technique that aims to decrease the surgical burden and enhance recovery.PubMed, MEDLINE, and EMBASE databases were searched for publications on mediastinoscope-assisted esophagectomies for esophageal cancer. The primary endpoint was a postoperative anastomotic leak, while secondary endpoints were assessment of harvested lymph nodes (LNs), blood loss, chyle leak, hospital length of stay (LOS), operative (OR) time, pneumonia, wound infection, mortality, and microscopic positive margin (R1). The pooled event rate (PER) and pooled mean were calculated for binary and continuous outcomes respectively.Twenty-six out of the 2274 searched studies were included. The pooled event rate (PER) for anastomotic leak was 0.145 (0.1144; 0.1828). The PERs for chyle leak, recurrent laryngeal nerve injury/hoarseness, postoperative pneumonia, wound infection, early mortality, postoperative morbidity, and microscopically positive (R1) resection margins were 0.027, 0.185, 0.09, 0.083, 0.020, 0.378, and 0.037 respectively. The pooled means for blood loss, hospital stay, operative time, number of total harvested LNs, and number of harvested thoracic LNs were 159.209, 15.187, 311.116, 23.379, and 15.458 respectively.Mediastinoscopic esophagectomy is a promising minimally invasive technique, avoiding thoracotomy, patient repositioning, and lung manipulation; thus allowing for shorter surgery, decreased blood loss, and decreased postoperative morbidity. It can also be reliable in terms of oncological safety and LN dissection.© 2023. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.