背景：疲劳是癌症康复者最常见的症状，癌相关疲劳（CRF）可能在癌症护理过程中的任何时候发生。多种因素对CRF的发展和严重程度做出贡献，包括癌症类型、治疗、其他症状的存在、合并症和药物副作用。在临床上，增加身体活动、提高睡眠质量和识别睡眠障碍是管理CRF的关键。不幸的是，肺癌幸存者中很少有人认识到、评估或治疗CRF，尽管这种症状比其他癌症更常见和严重。因此，需要增加对CRF的认识和理解，以改善肺癌幸存者的健康相关生命质量。 目标：1）确定并优先考虑知识和研究空白，2）制定并优先考虑评估在肺癌幸存者中CRF机制、诊断和治疗方法的研究问题。 方法：我们组织了一个多学科专家小组，审查了有关CRF的现有文献，重点关注肺癌患者身体活动、康复和睡眠障碍的影响。我们使用了一个三轮修正Delphi过程来优先考虑研究问题。 结果：本声明确定了以下知识空白：1）在肺癌幸存者中检测和诊断评估CRF；2）身体活动和康复的时机、目标和实施；3）评估和治疗睡眠障碍和睡眠紊乱以减轻CRF。最后，我们呈现了小组的32个研究问题和七个最终优先考虑的问题。 结论：本声明提供了一个优先考虑的研究议程，以1）推动临床和研究工作，并2）增加肺癌幸存者对CRF的认识。

Background: Fatigue is the most common symptom among cancer survivors. Cancer-related fatigue (CRF) may occur at any point in the cancer care continuum. Multiple factors contribute to CRF development and severity, including cancer type, treatments, presence of other symptoms, comorbidities, and medication side effects. Clinically, increasing physical activity, enhancing sleep quality, and recognizing sleep disorders are integral to managing CRF. Unfortunately, CRF is infrequently recognized, evaluated, or treated in lung cancer survivors despite more frequent and severe symptoms than in other cancers. Therefore, increased awareness and understanding of CRF are needed to improve health-related quality of life in lung cancer survivors. Objectives: 1) To identify and prioritize knowledge and research gaps and 2) to develop and prioritize research questions to evaluate mechanistic, diagnostic, and therapeutic approaches to CRF among lung cancer survivors. Methods: We convened a multidisciplinary panel to review the available literature on CRF, focusing on the impacts of physical activity, rehabilitation, and sleep disturbances in lung cancer. We used a three-round modified Delphi process to prioritize research questions. Results: This statement identifies knowledge gaps in the 1) detection and diagnostic evaluation of CRF in lung cancer survivors; 2) timing, goals, and implementation of physical activity and rehabilitation; and 3) evaluation and treatment of sleep disturbances and disorders to reduce CRF. Finally, we present the panel's initial 32 research questions and seven final prioritized questions. Conclusions: This statement offers a prioritized research agenda to 1) advance clinical and research efforts and 2) increase awareness of CRF in lung cancer survivors.