COVID-19 大流行在美国和全球继续造成重大的社会经济变动。唯一有效的干预措施是采取高效的大规模疫苗接种计划来预防 COVID-19 疫苗，这对于公共卫生系统的支持和公众的信任和接受度至关重要。根据不同的地缘社会背景，疫苗犹豫被认为是最大的障碍之一。 Overton Brooks VA 对癌症患者进行了一项调查，以探索 COVID-19 疫苗犹豫的人口统计学模式和原因。电话调查设计，调查地点为阿肯色州-路易斯安那州-得克萨斯州（ArkLATX）地区的五个血液病学-肿瘤诊所。研究对象为240名患有癌症的退伍军人的随机样本。干预措施：询问退伍军人是否有兴趣接种疫苗，并说明拒绝的原因。要求他们将原因归类为安全性、有效性、信息不足、反对任何疫苗、不想成为第一个接种者或其他/解释。结果：参与者的中位年龄为71岁。调查对象中92%为男性，40%为黑人，59%为白人。79%的人想接种疫苗。在拒绝接种疫苗的退伍军人中，原因是担心安全问题（33%）、不想成为第一个接种者（33%）、反对疫苗（14%）和信息不足（8%）。没有人提到有效性方面存在的担忧。其他原因（12%）包括认为没有接种疫苗的理由、引用之前接种疫苗的严重反应和对政府表示不信任。与接受或拒绝疫苗的老兵在人口特征方面没有统计学差异。调查表明大多数 ArkLATX 的癌症患者退役军人愿意接种 COVID-19 疫苗。疫苗犹豫的主要原因似乎是信息问题，包括安全问题、信息不足和没有接种疫苗的理由。通过提供适当的信息和咨询，这些障碍可以被潜在地克服。

Context: The COVID-19 pandemic continues to be a major socioeconomic disruptor in the U.S. and around the globe. The only intervention that has a far-reaching impact is the adoption of an efficient large-scale vaccination campaign with the highly effective COVID-19 vaccines. While the success of this strategy is predicated on the presence of adequate healthcare systems capacity, it also hinges on the trust and acceptance of the public. Vaccine hesitancy, which varies by the geosocial context, is considered a top obstacle. Objective: The Overton Brooks VA embarked on a survey to explore the demographic patterns and reasons for COVID-19 vaccination hesitancy among cancer patients. Study Design: phone survey. Setting: five Hematology-Oncology clinics across the ArkLATX. Population: random sample of 240 veterans with cancer. Intervention: Veterans were asked whether they are interested in getting vaccinated and to state the reason if they declined. They were asked to categorize the reason as relating to safety, efficacy, inadequate Information, aversion to any vaccine, not wanting to be the first, or other/explain. Outcome Measures: 1. Descriptive statistics of those who want and those who decline the vaccine. 2. Determine the impact of demographic factors on COVID19 vaccine hesitancy. Results: The median age was 71 years. The participants were 92% males and 40% Black vs 59% White. Seventy nine percent wanted to get vaccinated. Among the veterans that declined (21%), the reasons were due to concerns about safety (33%), not wanting to be the first (33%), anti-vaxxer stance (14%), and inadequate information (8%). No one cited concerns about efficacy as a reason. Other reasons (12%) included seeing no reason for the vaccination, citing severe reactions to prior vaccines, and voicing mistrust of the government. There were no statistical differences between veterans that approved or declined the vaccine with respect to demographic characteristics. Conclusions: This survey indicates that the majority of ArkLATX veterans with cancer are willing to be vaccinated against COVID-19. The major reasons behind vaccine hesitancy seem to be information problems consisting of questions about safety, inadequate information, and seeing no reason for the vaccine. Such barriers can be potentially circumvented by providing the appropriate information and counseling.© 2021 Annals of Family Medicine, Inc.