在一个老龄化的社会里，慢性疾病不断恶化增加了患者和医疗系统的负担。利用包括社交网络（SNS）在内的在线健康信息，如 Facebook 和 YouTube，可能在慢性疾病的自我管理和健康促进方面对互联网用户起重要作用。该研究旨在改善通过互联网促进可靠信息的访问，以便慢性疾病的自我管理，并识别面临健康互联网使用障碍的人群，我们研究了慢性疾病和与在线健康信息获取和 SNS 使用有关的特征。该研究使用了2020年 INFORM 研究的数据，这是一个全国代表性的横断面邮寄调查，使用自填问卷调查。依赖变量是在线健康信息获取和 SNS 使用。在线健康信息获取使用一个问题评估，即受访者是否使用互联网查找健康或医疗信息。 SNS 使用通过询问以下四个方面来评估：访问 SNS，在 SNS 上分享健康信息，在线日记或博客中写作，以及观看 YouTube 上与健康相关的视频。自变量是8种慢性疾病。其他自变量是性别、年龄、教育状况、工作、婚姻状况、家庭收入、健康素养和自报健康状况。我们进行了多种变量 logistic 回归模型，根据所有自变量进行调整，以研究慢性疾病和其他变量与在线健康信息获取和 SNS 使用的关联。最终用于分析的样本包括2481名互联网用户。24.5%、10.1%、7.7%和7.2%的受访者报告患有高血压或高血压、慢性肺部疾病、抑郁或焦虑症和癌症。相较于没有癌症的人群，癌症患者的在线健康信息搜索的几率比值比为2.19（95% CI 1.47-3.27），而抑郁或焦虑症患者的几率比值比为2.27（95% CI 1.46-3.53）。此外，与没有这些疾病的人群相比，患有慢性肺部疾病的人群在观看与健康相关的 YouTube 视频方面的几率比值比为1.42（95% CI 1.05-1.93）。女性、年轻人、教育水平较高和健康素养高的人与在线健康信息搜索和 SNS 使用呈正相关。对于患癌症的患者，促进访问可靠癌症相关信息的网站以及使患有慢性肺病的患者能够访问提供可靠信息的 YouTube 视频的策略可能有益于管理这些疾病。此外，改善在线环境以鼓励男性、老年人、教育水平较低的互联网用户和健康素养较低的人访问在线健康信息至关重要。 ©Seigo Mitsutake，Yoshimitsu Takahashi，Aki Otsuki，Jun Umezawa，Akiko Yaguchi-Saito，Junko Saito，Maiko Fujimori，Taichi Shimazu，INFORM 研究小组。最初发表于《医学互联网研究杂志》（https://www.jmir.org），2023年2月3日。

In an aging society, worsening chronic diseases increase the burden on patients and the health care system. Using online health information including health information via social networking sites (SNSs), such as Facebook and YouTube, may play an important role in the self-management of chronic diseases and health promotion for internet users.This study aims to improve strategies for promoting access to reliable information for the self-management of chronic diseases via the internet, and to identify populations facing barriers to using the internet for health, we examined chronic diseases and characteristics associated with online health information seeking and the use of SNSs.This study used data from the INFORM Study 2020, which was a nationally representative cross-sectional postal mail survey conducted using a self-administered questionnaire in 2020. The dependent variables were online health information seeking and SNS use. Online health information seeking was assessed using 1 question about whether respondents used the internet to find health or medical information. SNS use was assessed by inquiring about the following 4 aspects: visiting SNSs, sharing health information on SNSs, writing in an online diary or blog, and watching a health-related video on YouTube. The independent variables were 8 chronic diseases. Other independent variables were sex, age, education status, work, marital status, household income, health literacy, and self-reported health status. We conducted a multivariable logistic regression model adjusted for all independent variables to examine the associations of chronic diseases and other variables with online health information seeking and SNS use.The final sample for analysis comprised 2481 internet users. Hypertension or high blood pressure, chronic lung diseases, depression or anxiety disorder, and cancer were reported by 24.5%, 10.1%, 7.7%, and 7.2% of respondents, respectively. The odds ratio of online health information seeking among respondents with cancer was 2.19 (95% CI 1.47-3.27) compared with that among those without cancer, and the odds ratio among those with depression or anxiety disorder was 2.27 (95% CI 1.46-3.53) compared with that among those without. Further, the odds ratio for watching a health-related YouTube video among those with chronic lung diseases was 1.42 (95% CI 1.05-1.93) compared with that among those without these diseases. Women, younger age, higher level of education, and high health literacy were positively associated with online health information seeking and SNS use.For patients with cancer, strategies for promoting access to websites with reliable cancer-related information as well as access among patients with chronic lung diseases to YouTube videos providing reliable information may be beneficial for the management of these diseases. Moreover, it is important to improve the online environment to encourage men, older adults, internet users with lower education levels, and those with low health literacy to access online health information.©Seigo Mitsutake, Yoshimitsu Takahashi, Aki Otsuki, Jun Umezawa, Akiko Yaguchi-Saito, Junko Saito, Maiko Fujimori, Taichi Shimazu, INFORM Study Group. Originally published in the Journal of Medical Internet Research (https://www.jmir.org), 02.03.2023.