研究动态
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据研究表明,Phyllanthus emblica(乌榄)果是一种富含多酚的水果,其在口腔管理方面具有潜在的益处。

Phyllanthus emblica fruits: a polyphenol-rich fruit with potential benefits for oral management.

发表日期:2023 Aug 02
作者: Gefei Li, Qiang Yu, Mengqi Li, Dingkun Zhang, Ji Yu, Xiaohan Yu, Chenxi Xia, Junzhi Lin, Li Han, Haozhou Huang
来源: ANTIOXIDANTS & REDOX SIGNALING

摘要:

菠萝蜜果(学名:Phyllanthus emblica Linn.)主要生长在热带和亚热带地区,因其药食同源的特性而闻名。它具有独特的风味、丰富的营养成分以及强效的抗氧化、抗炎、抗癌和免疫调节作用。根据越来越多的科学和临床证据,这种果实在口腔健康管理领域显示出显著的应用和开发潜力。通过补充维生素、超氧化物歧化酶(SOD)和其他营养物质,减少各种口腔病原体的毒力表达,预防由氧化应激引起的组织和粘膜损伤等。菠萝蜜果可促进唾液分泌,调节口腔微生态平衡,预防和早期治疗口腔癌,促进牙槽骨重塑和帮助粘膜伤口愈合。因此,在预防和治疗常见口腔疾病方面,它起到了特定的作用,并产生了令人惊喜的效果。例如,增强牙周病治疗中洗牙和根面平整的效果,缓解放射治疗引起的口腔癌粘膜炎症,并调节血糖代谢以缓解口腔不适感。在本文中,我们系统地对菠萝蜜果在口腔健康管理中的应用进行了最新研究的综述,并基于其化学组成和特性,探讨了面临的挑战和未来研究方向。
The fruit of Phyllanthus emblica Linn., which mainly grows in tropical and subtropical regions, is well-known for its medicine and food homology properties. It has a distinctive flavor, great nutritional content, and potent antioxidant, anti-inflammatory, anti-cancer and immunoregulatory effects. According to an increasing amount of scientific and clinical evidence, this fruit shows significant potential for application and development in the field of oral health management. Through the supplementation of vitamins, superoxide dismutase (SOD) and other nutrients reduce virulence expression of various oral pathogens, prevent tissue and mucosal damage caused by oxidative stress, etc. Phyllanthus emblica fruit can promote saliva secretion, regulate the balance of the oral microecology, prevent and treat oral cancer early, promote alveolar bone remodeling and aid mucosal wound healing. Thus, it plays a specific role in the prevention and treatment of common oral disorders, producing surprising results. For instance, enhancing the effectiveness of scaling and root planing in the treatment of periodontitis, relieving mucosal inflammation caused by radiotherapy for oral cancer, and regulating the blood glucose metabolism to alleviate oral discomfort. Herein, we systematically review the latest research on the use of Phyllanthus emblica fruit in the management of oral health and examine the challenges and future research directions based on its chemical composition and characteristics.