碳点在口腔健康领域的应用:综述评估
The applications of carbon dots in oral health: A scoping review.
发表日期:2023 Aug 02
作者:
Cuicui Fu, Henk S Brand, Floris J Bikker
来源:
ORAL DISEASES
摘要:
本篇综述旨在概述碳点(CDs)在口腔健康目的中的研究和潜在应用。在PubMed和Web of Science数据库中进行了系统文献检索(截至2023年2月)。两位共同作者独立选择了发表的作品,并根据PRISMA声明提取了数据。包括应用CDs进行口腔健康目的的研究。在152篇文章中,最终选择了19篇文章。其中8项研究探讨了CDs对口腔致病菌等的抗菌效果,8项研究探索了CDs在口腔癌相关应用方面的适用性,还有3项研究探讨了CDs在口腔健康方面的细胞分化和组织再生方面的应用。研究结果表明,CDs在口腔健康方面具有很大潜力,特别是通过增加活性氧物种诱导细菌杀灭,通过光动力疗法效应杀灭口腔癌细胞,并诱导牙髓和牙周骨再生。研究结果表明,CDs在未来可以用于各种口腔健康目的。此外,这些结果强调了CDs的广泛适用性,超越了口腔健康的界限。© 2023 The Authors. Oral Disorders,由Wiley Periodicals LLC出版。
This scoping review aims to provide an overview of the research and potential applications of carbon dots (CDs) for oral health purposes.Systematic literature searches were performed on PubMed and Web of Science databases (up to February 2023). Two co-authors selected the published works independently and extracted the data in accordance with the PRISMA statement. Studies with the application of CDs for oral health purposes were included.Among 152 articles, 19 articles were finally selected. Eight studies investigated the anti-microbial effects of CDs against, for example, oral pathogens, eight studies explored the applicability of CDs in relation to oral cancer, and three studies investigated CDs in relation to cell differentiation and tissue regeneration in oral health. The studies showed the promising potential of CDs in oral health, particularly for inducing bacterial killing by increasing reactive oxygen species, killing oral cancer cells via photodynamic therapeutic effects, and inducing dental pulp and periodontal bone regeneration.The findings show that CDs have the potential to be utilized in the future for various oral health purposes. Besides, these results underline the broad-spectrum applicability of CDs, crossing the borders of oral health.© 2023 The Authors. Oral Diseases published by Wiley Periodicals LLC.