研究动态
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营养状态与晚期咽喉癌或喉癌手术患者术后并发症的关系研究。

Nutritional status and post-operative complications in patients undergoing surgery for advanced pharyngeal or laryngeal cancer.

发表日期:2023 Aug 03
作者: Teresa Brown, Anna Edwards, Alice Pashley, Belinda Lehn, Sarju Vasani, Robert Hodge, Judith Bauer
来源: Food & Function

摘要:

营养不良是头颈癌手术后预后结局的重要预测指标,然而,有限的研究利用经过验证的营养评估工具准确评估风险。本研究旨在确定营养状况与头颈癌患者接受喉切除术、咽切除术或咽喉切除术后并发症和住院时间之间的关系。符合条件的澳大利亚三级医院头颈癌患者(n = 40)被纳入这项回顾性队列研究。营养状况由营养师在入院时利用经过验证的主观全面评定工具进行评估。通过回顾性病历复查收集临床结局数据,包括住院时间和术后并发症。术前营养不良发生率为40%。与营养良好的患者相比,营养不良患者出现任意类型的并发症(57% vs 44%,p = 0.013)和压力性损伤(86% vs 14%,p = 0.011)的发生率更高。与营养不良患者相比,营养良好的患者的住院时间中位数更短且具有临床重要性(17.5天 vs 20天)。早期识别和管理营养不良对于减少术后并发症风险和缩短住院时间至关重要,并应视为康复前计划的关键组成部分。© 2023. 版权所有.
Malnutrition is an important prognostic indicator of post-operative outcomes in patients undergoing surgery for head and neck cancer, however, limited studies utilize validated nutrition assessment tools to accurately assess risk. The aim of this study was to determine the relationship between nutritional status on post-operative complications and length of stay for patients undergoing either a laryngectomy, pharyngectomy or pharyngolaryngectomy for head and neck cancer.Patients with head and neck cancer undergoing a laryngectomy, pharyngectomy or pharyngolaryngectomy at a tertiary hospital in Australia were eligible for this retrospective cohort study (n = 40). Nutritional status was assessed by the dietitian on admission using the validated Subjective Global Assessment tool. Clinical outcomes were collected via retrospective chart review and included length of stay and post-operative complications.Pre-operative malnutrition incidence was 40%. Malnourished patients had higher incidences of any type of complication (57% vs 44%, p = 0.013) and pressure injury (86% vs 14%, p = 0.011) compared to well-nourished patients. Well-nourished patients had a clinically important shorter median length of stay compared to malnourished patients (17.5 vs 20 days).Early identification and management of malnutrition is essential to minimize risk of post-operative complications and reduce length of stay and should be considered a key component of prehabilitation programs.© 2023. Crown.