肝脏的炎症性假瘤。
Inflammatory Pseudotumor of the Liver.
发表日期：2023 Sep
作者：
Donghai Wang, Joseph Misdraji
来源：
Cellular & Molecular Immunology
摘要：
肝炎性假瘤（IPT）是由成纤维细胞或肌纤维细胞组成的肿块，其中伴有淋巴细胞、浆细胞和组织细胞的密集炎症浸润。这些病变被认为是对感染机体的过度反应，尽管在大多数情况下致病因子是未知的。在特定情况下，病理学家应考虑使用辅助技术排除特定感染，如结核菌、念珠菌或梅毒。IgG4相关疾病可能导致富含浆细胞的IPT。最后，真正的肿瘤可以模仿IPT，并且必须通过适当的辅助研究排除，包括炎性肌纤维母细胞瘤、滤泡树突细胞瘤、炎性肾血管平滑肌脂肪瘤、霍奇金淋巴瘤和炎性肝细胞癌。版权© 2023 Elsevier Inc. 保留所有权利。
Hepatic inflammatory pseudotumor (IPT) describes a mass lesion composed of fibroblasts or myofibroblasts with a dense inflammatory infiltrate comprising lymphocyte, plasma cells, and histiocytes. These lesions are presumed to be an exuberant response to an infectious organism, although in most cases the causative agent is unknown. In specific circumstances, pathologists should consider ancillary techniques to exclude specific infections, such as mycobacteria, Candida, or syphilis. IgG4-related disease may cause a plasma-cell rich IPT. Finally, true neoplasms can mimic IPTs and must be excluded with appropriate ancillary studies, including inflammatory myofibroblastic tumor, follicular dendritic cell tumor, inflammatory angiomyolipoma, Hodgkin lymphoma, and inflammatory hepatocellular carcinoma.Copyright © 2023 Elsevier Inc. All rights reserved.