中国菝葜(Smilax china L.): 它的植物学、民族药理学、植物化学、药理活性、实际和潜在应用的综述。
Smilax china L.: A review of its botany, ethnopharmacology, phytochemistry, pharmacological activities, actual and potential applications.
发表日期:2023 Aug 02
作者:
Meng Wang, Qian-Xiang Bai, Xiu-Xi Zheng, Wen-Jing Hu, Shuang Wang, Hai-Peng Tang, Ai-Qi Yu, Bing-You Yang, Hai-Xue Kuang
来源:
ANTIOXIDANTS & REDOX SIGNALING
摘要:
中国菝葜(Smilax china L.)是一种广泛使用的传统中药,在中国被称为巴桥(Baqia)。它被用于治疗各种炎症性疾病,尤其是盆腔炎。本文旨在对菝葜的民族药理学、植物化学、药理作用以及实际和潜在应用的研究进展进行最新综述。同时,还讨论了该植物未来研究的可能动向和前景。本文以"Smilax china L."和"S. china"作为关键词,通过电子检索(Elsevier、PubMed、ACS、CNKI、Google Scholar、Baidu Scholar、Web of Science)、相关书籍和有关中国草药的经典文献收集了有关中国菝葜植物的相关信息。从中国菝葜中分离和鉴定出134种化学成分,其中甾体皂苷和黄酮类化合物是主要类群。中国菝葜以其活性化合物表现出广泛的生物活性,包括抗炎、抗癌、抗氧化、解毒尼古丁、抗糖尿病、抗肥胖、抗高尿酸血症、抗高血压、促进皮肤伤口和屏障修复以及抗菌活性。此外,中国菝葜还应用于食品工业和检测技术等其他领域。根据对中国菝葜植物的现有植物化学研究的综述,中国菝葜植物提取物的结构表征仍然可以是未来研究的重点。体外和体内的药理研究已经证明了中国菝葜提取物的一些传统用途,但其他传统用途仍需进一步研究加以确认。版权所有 © 2023 Elsevier B.V.发表。
Smilax china L., an extensively used traditional Chinese medicine, is known as Baqia in China. It has been used to treat various inflammatory disorders, particularly pelvic inflammation.The present paper aims to provide an up-to-date review at the advancements of the investigations on the ethnopharmacology, phytochemistry, pharmacological effect and actual and potential applications of S. china. Besides, the possible tendency and perspective for future research of this plant are discussed, as well.This article uses "Smilax china L." "S. china" as the keyword and collects relevant information on Smilax china L. plants through electronic searches (Elsevier, PubMed, ACS, CNKI, Google Scholar, Baidu Scholar, Web of Science), relevant books, and classic literature about Chinese herb.134 chemical constituents, among which steroid saponins and flavonoids are the predominant groups, have been isolated and identified from S. china. S. china with its active compounds is possessed of wide-reaching biological activities, including anti-inflammatory, anti-cancer, anti-oxidant, detoxify nicotine, anti-diabetes, anti-obesity, anti-hyperuricaemia, anti-hypertension, promoting skin wound and barrier repair and anti-bacterial activity. Besides, S. china is also applied to other fields, such as food industry and detection technology.Based on the review of the existing phytochemical studies on Smilax china L., the structural characterization of Smilax china L. extract can continue to be the focus of future research. Pharmacological studies in vitro and in vivo have demonstrated some of the traditional uses of Smilax china L. extract, while other traditional uses still need to be confirmed by research.Copyright © 2023. Published by Elsevier B.V.