一名持续升高血清前列腺特异性抗原水平的53岁男性（9.53 ng/mL）并反复进行阴性前列腺活检被推荐进行68Ga-PSMA-11正电子发射计算机断层扫描（PET/CT）。PET/CT显示前列腺局部摄取增加，提示局部前列腺癌。此外，PET/CT还显示气道支气管树弥漫性摄取增加，怀疑是良性病因。鉴于前一周哮喘急性加重的临床史，进一步进行了补充研究，显示肺泡可呼出一氧化氮的病理性水平（92 ppb；参考值，<25 ppb）以及肺功能检查中轻度气道梗阻。这些发现确认哮喘是气道支气管PSMA摄取增加的发炎病因。 版权所有 © 2023 Wolters Kluwer Health, Inc. 保留所有权利。

A 53-year-old man with persisting increased serum prostate-specific antigen level (9.53 ng/mL) and repeated negative prostate biopsies was referred for a PET/CT with 68Ga-PSMA-11. The PET/CT revealed focal uptake in the prostate suggestive of localized prostate cancer. Incidentally, it also showed a diffuse uptake in the tracheobronchial tree suspicious for a benign etiology. Because of the clinical history of asthma exacerbation in the previous week, further supplementary studies were performed showing a pathological fractional exhaled nitric oxide level (92 ppb; reference values, <25 ppb) and mild airway obstruction in the spirometry. These findings confirmed asthma as an inflammatory etiology of the tracheobronchial PSMA uptake.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.