为了调查胆管癌手术后肝胃缺血性坏死引发肝脓肿的相关因素，收集了100例需要手术切除的胆管癌患者，并根据是否有肝脓肿将其分为试验组（53例肝脓肿患者）和对照组（47例无肝脓肿患者）。比较了以下相关因素：性别、年龄、体质指数（BMI）、入院时体温、病史持续时间、是否有糖尿病病史、病史时间、是否有肝胆管结石、绝对中性粒细胞计数、绝对淋巴细胞计数（ALC）、C-反应蛋白、血清白蛋白（ALB）、丙氨酸氨基转移酶（ALT）、天冬氨酸氨基转移酶（AST）、碱性磷酸酶（AKP）、直接胆红素（DBIL）、血清肌酐以及是否贫血。单变量分析显示BMI、年龄、性别、绝对淋巴细胞计数、血清ALB、AST和病史时间在两组之间有显著差异(P<0.05)。对上述影响因素进行多因素logistic回归分析后发现术后肝脓肿形成的独立影响因素是：ALC<1.1*10^9/L（P<0.001，OR=23.459，95% CI=8.529-64.576）、AST≥40 U/L（P=0.012，OR=3.946，95% CI=1.355-11.487）、病史时间≥21天（P=0.010，OR=4.028，95% CI=1.389-11.681）。ALC降低、AST增加和急性胆道感染的发生是与肝胆血管缺血性坏死相关的肝脓肿的独立因素。异常营养状况、年龄和性别也是肝脓肿的影响因素。

To investigate related factors of liver abscess associated with hepatobiliary ischemic necrosis after cholangiocarcinoma surgery, 100 patients with cholangiocarcinoma requiring surgical resection were collected and divided into a test group (53 patients with liver abscess) and a control group (47 patients without liver abscess) according to presence or absence of liver abscess. Related factors were compared: gender, age, body mass index (BMI), body temperature at admission, duration of medical history, presence or absence of a history of diabetes, time of medical history, presence or absence of hepatolithiasis, absolute neutrophil count, absolute lymphocyte count (ALC), C-reactive protein, serum albumin (ALB), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (AKP), direct bilirubin (DBIL), serum creatine, and presence or absence of anemia. Univariate analysis showed that BMI, age, gender, absolute lymphocyte count, serum ALB, AST, and time of medical history were significantly different between the two (P<0.05). Multivariate logistic regression analysis of the above influencing factors showed that independent influencing factors of postoperative liver abscess formation were: ALC<1.1*10^9/L (P<0.001, OR=23.459, 95% CI=8.529-64.576), AST≥40 U/L (P=0.012, OR=3.946, 95% CI=1.355-11.487), time of medical history≥21 days (P=0.010, OR=4.028, 95% CI=1.389-11.681). Decreased ALC, increased AST, and occurrence of acute biliary tract infection were independent factors for hepatobiliary ischemic necrosis-related liver abscess. Abnormal nutritional status, age, and gender were also the influencing factors of liver abscess.