本文发现了赫尔曼·穆勒(Hermann Muller)的六个主要概念性科学错误的发生，并描述了这些错误如何导致了线性无阈值(LNT)剂量响应，该响应在全球范围内被历史性地用于化学致癌物和电离辐射的癌症风险评估。本文展示了穆勒在环境运动中起到的重要作用，影响了至今已故的他人的风险评估政策和实践。本文对当代研究提供了支持，显示了LNT模型在癌症风险评估中存在显著局限。版权所有©2023 Elsevier B.V发表。

This paper identifies the occurrence of six major conceptual scientific errors of Hermann Muller and describes how these errors led to the creation of the linear no-threshold (LNT) dose response historically used worldwide for cancer risk assessments for chemical carcinogens and ionizing radiation. The paper demonstrates the significant role that Muller played in the environmental movement, affecting risk assessment policies and practices that are in force even now a half century following his death. This paper lends support to contemporary research that shows significant limitations of the LNT model for cancer risk assessment.Copyright © 2023. Published by Elsevier B.V.