目的: 探讨与热死亡相关的长链非编码RNA (lncRNA) 表达在皮肤黑色素瘤（CM）患者的预后和抗肿瘤免疫中是否存在差异。方法: 进行了一系列分析以建立预后风险模型并验证其准确性。进一步进行免疫相关分析以评估免疫状况、肿瘤微环境和预后风险模型之间的关联。结果：确定了8个与预后相关的热死亡相关的lncRNA，并应用其建立了预后风险模型。低风险组的总体生存率较高。结论：建立的预后风险模型在CM患者的预后预测方面具有更好的预测能力，并为CM提供了新的可能治疗靶点。

Aims: To explore whether the expression of pyroptosis-related lncRNAs makes a difference in the prognosis and antitumor immunity of cutaneous melanoma (CM) patients. Methods: A series of analyses were conducted to establish a prognostic risk model and validate its accuracy. Immune-related analyses were performed to further assess the associations among immune status, tumor microenvironment and the prognostic risk model. Results: Eight pyroptosis-related lncRNAs relevant to prognosis were ascertained and applied to establish the prognostic risk model. The low-risk group had a higher overall survival rate. Conclusion: The established prognostic risk model presents better prediction ability for the prognosis of CM patients and provides new possible therapeutic targets for CM.