研究动态
Articles below are published ahead of final publication in an issue. Please cite articles in the following format: authors, (year), title, journal, DOI.

黑人青少年和年轻成年癌症幸存者患慢性健康问题的风险过高。

Excess risk of chronic health conditions in Black adolescent and young adult cancer survivors.

发表日期:2023 Aug 14
作者: Amy M Berkman, Eunju Choi, Christabel K Cheung, John M Salsman, Susan K Peterson, Clark R Andersen, Qian Lu, J A Livingston, Aryce Battle, Michelle A T Hildebrandt, Susan K Parsons, Michael E Roth
来源: DIABETES & METABOLISM

摘要:

美国年轻人和青少年(在诊断时年龄为15-39岁)癌症幸存者的人口正在增加。先前的研究已经发现,在种族少数群体中,包括黑人幸存者在内的幸存者与白人幸存者相比,在生存和健康结果方面存在种族和民族差异。然而,应该在民族少数群体内,在有无幼年和青少年(AYA)癌症史的相同种族或民族的个体之间进行比较,以充分了解癌症诊断与社会经济地位(SES)和健康结果之间的关联。从国家健康访问调查(2009-2018)的自述数据中确定非西班牙裔黑人AYA癌症幸存者和非西班牙裔黑人年龄和性别匹配的对照组。使用卡方检验比较幸存者和对照组之间的SES因素和慢性疾病患病率。使用加权调查逻辑回归模型确定幸存者和对照组之间的SES因素对慢性疾病的患病率的几率。评估每个变量与癌症组之间的相互作用。 共包括445名幸存者和4450名对照组。与对照组相比,幸存者较少结婚,家庭年收入>45K美元,完成学士学位或更高,并拥有私人医疗保险。幸存者患有至少一种(概率比(OR):7.02,P<0.001)和≥3种(OR:4.44,P<0.001)慢性疾病的几率高于对照组。幸存者患有所评估的每一种慢性疾病(包括心血管疾病、糖尿病和高血压)的几率较高。与所有SES变量相比,幸存者患有慢性疾病的几率较对照组高。 在青少年和年轻成年期被诊断为癌症与黑人人群内不良SES结果和共患病的几率增加相关,从而进一步加剧了现有的差距。 黑人AYA癌症幸存者在癌症治疗后发展慢性健康问题的风险非常高,因此需要采取干预措施以改善该人群的长期健康结果。 ©2023作者,独家授权给斯普林格科学+商业媒体有限责任公司部分斯普林格自然集团。
The US population of adolescent and young adult (age 15-39 years at diagnosis) cancer survivors is growing. Previous studies have identified racial and ethnic disparities in survival and health outcomes in racially minoritized survivors, including Black survivors, compared with White survivors. However, comparisons should be made between those of the same race or ethnicity with and without a history of AYA cancer to fully understand the association of a cancer diagnosis with socioeconomic status (SES) and health outcomes within a minoritized population.Non-Hispanic Black AYA cancer survivors and non-Hispanic Black age- and sex-matched controls were identified from self-reported data from the National Health Interview Survey (2009-2018). SES factors and chronic health conditions prevalence were compared between survivors and controls using chi-square tests. Survey-weighted logistic regression models were used to determine odds of chronic conditions by SES factors within and between survivors and controls. Interactions between each variable and cancer group were assessed.A total of 445 survivors and 4450 controls were included. Survivors were less likely than controls to be married, have family income >45K/year, have completed a bachelor's degree or higher, and have private insurance. Survivors had higher odds than controls of having at least one (odds ratio (OR): 7.02, p<0.001) and ≥3 (OR: 4.44, p<0.001) chronic conditions. Survivors had higher odds of each chronic condition assessed including cardiovascular disease, diabetes, and hypertension. Survivors had higher odds of having chronic health conditions compared with controls across all SES variables.A cancer diagnosis during adolescence and young adulthood is associated with poor SES outcomes and increased odds of comorbidities within the Black population, thus further exacerbating existing disparities.Black AYA cancer survivors have a very high risk of developing chronic health conditions after cancer treatment and interventions are needed to improve long-term health outcomes for this population.© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.