为了评估儿童人群中与冷冻消融有关的并发症，并回顾预防这些并发症的措施。回顾性研究包括在儿童人群中进行的所有图像引导冷冻消融。分析了立即和延迟的并发症，并确定了使用的不同保护措施和随访的临床结果。使用最大似然计算并发症百分比的点估计，并使用Clopper-Pearson确切方法计算真实百分比的95%置信区间。对68名患者进行了87次消融（年龄范围为2-18岁，平均12.4岁），用于非肿瘤性病变（70%）和肿瘤性病变（30%）。导致并发症的消融百分比为18%（95%置信区间为11%至28%）。其中，5%（95%CI 1%至11%）为3级并发症，14%（95%CI 7%至23%）为2级并发症。27.6%的消融（n = 24）进行了热保护。平均临床随访时间为348天。儿童人群中的冷冻消融相对安全，每次消融的重大并发症率为5%。可以考虑采取热保护措施来减轻这些并发症。© 2023. Springer Science+Business Media, LLC, Springer Nature和欧洲心血管和介入放射学学会（CIRSE）。

To evaluate complications associated with cryoablation in a pediatric population and review preventive measures to mitigate these complications.Retrospective study including all the image guided cryoablations performed on pediatric population. Immediate and delayed complications were analyzed, and we identified the different protective measures used and the clinical outcomes from follow-up. Point estimates for the percentage of complications were calculated by maximum likelihood, and 95% confidence intervals for the true percentages were calculated using the Clopper-Pearson exact method.Eighty-seven ablations were performed on 68 patients (age range of 2-18 years, mean 12.4 years) for non-neoplastic (70%) and neoplastic (30%) lesions. The percentage of ablations resulting in complications was 18% (95% confidence interval (CI) 11% to 28%). Of these, 5% (95% CI 1% to 11%) were grade 3 complications, and 14% (95% CI 7% to 23%) were grade 2 complications. Thermal protection was performed in 27.6% of ablations (n = 24). The mean clinical follow-up duration was 348 days.Cryoablation in pediatric patients is relatively safe, with a major complication rate per ablation of 5%. Thermal protective measures can be considered to mitigate these complications.© 2023. Springer Science+Business Media, LLC, part of Springer Nature and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE).