因此，本研究的目的是比较通过使用单回声和双回声技术（UTE-MRISingle和UTE-MRIDual）和薄层CT获得的超短TE（UTE）的肺MRIs在定量区分非侵袭性和微创性腺癌与其他疑似恶性肺癌的能力。本回顾性研究纳入了90例经病理诊断为IA期肺癌的患者，这些患者接受了薄层标准剂量CT、UTE-MRISingle和UTE-MRIDual、手术治疗和病理检查。评估了每个结节的最大尺寸（Dlong）、实性部分（实性Dlong）和实变/肿瘤（C/T）比值。使用双侧学生t检验比较了每种方法得到的所有指标在非侵袭性和微创性腺癌与其他肺癌之间的差异。进行了基于ROC的阳性测试，以确定区分非侵袭性或微创性腺癌（MIA）与其他肺癌的所有可行阈值。然后，使用McNemar检验比较了敏感性、特异性和准确性。每个指标在两组之间都显示出显著差异（p < 0.0001）。UTE-MRIDual第2个回声的实性Dlong和CTMediastinal的特异性和准确性均明显高于UTE-MRISingle和UTE-MRIDual第1个回声以及除CTMediastinal之外的所有C/T比值（p < 0.05）。此外，实性Dlong和C/T比值的特异性和准确性均明显高于每种方法的Dlong（p < 0.05）。UTE的肺部MRI至少与薄层CT具有同等价值，可对非侵袭性和微创性腺癌与其他IA期肺癌进行定量区分。对于IA期肺癌患者，UTE的肺部MRI对非侵袭性和微创性腺癌与其他肺癌的定量区分能力至少等同于薄层CT。与病理学检查的最大尺寸（Dlong）和实性成分（实性Dlong）的相关性极好，对于所有指标（0.95 ≤ r ≤ 0.99，p < 0.0001）。通过所有方法获得的经病理学检查的Dlong和实性Dlong在非侵袭性和微创性腺癌与其他肺癌之间显示出显著差异（p < 0.0001）。实性肿瘤成分最准确地由UTE-MRIDual第2个回声和CTMediastinal测量，而杯状磨砂成分则通过UTE-MRIDual第1个回声和CTlung以高准确性显示。在C/T阈值为0.5时，UTE-MRIDual以100%的敏感性和87.5%的特异性预测肿瘤的侵袭性。 © 2023. 作者，独家授权于欧洲放射学学会。

The purpose of this study was thus to compare capabilities for quantitative differentiation of non- and minimally invasive adenocarcinomas from other of pulmonary MRIs with ultra-short TE (UTE) obtained with single- and dual-echo techniques (UTE-MRISingle and UTE-MRIDual) and thin-section CT for stage IA lung cancer patients.Ninety pathologically diagnosed stage IA lung cancer patients who underwent thin-section standard-dose CT, UTE-MRISingle, and UTE-MRIDual, surgical treatment and pathological examinations were included in this retrospective study. The largest dimension (Dlong), solid portion (solid Dlong), and consolidation/tumor (C/T) ratio of each nodule were assessed. Two-tailed Student's t-tests were performed to compare all indexes obtained with each method between non- and minimally invasive adenocarcinomas and other lung cancers. Receiver operating characteristic (ROC)-based positive tests were performed to determine all feasible threshold values for distinguishing non- or minimally invasive adenocarcinoma (MIA) from other lung cancers. Sensitivity, specificity, and accuracy were then compared by means of McNemar's test.Each index showed significant differences between the two groups (p < 0.0001). Specificities and accuracies of solid Dlong for UTE-MRIDual2nd echo and CTMediastinal were significantly higher than those of solid Dlong for UTE-MRISingle and UTE-MRIDual1st echo and all C/T ratios except CTMediastinal (p < 0.05). Moreover, the specificities and accuracies of solid Dlong and C/T ratio were significantly higher than those of Dlong for each method (p < 0.05).Pulmonary MRI with UTE is considered at least as valuable as thin-section CT for quantitative differentiation of non- and minimally invasive adenocarcinomas from other stage IA lung cancers.Pulmonary MRI with UTE's capability for quantitative differentiation of non- and minimally invasive adenocarcinomas from other lung cancers in stage IA lung cancer patients is equal or superior to that of thin-section CT.• Correlations were excellent for pathologically examined nodules with the largest dimensions (Dlong) and a solid component (solid Dlong) for all indexes (0.95 ≤ r ≤ 0.99, p < 0.0001). • Pathologically examined Dlong and solid Dlong obtained with all methods showed significant differences between non- and minimally invasive adenocarcinomas and other lung cancers (p < 0.0001). • Solid tumor components are most accurately measured by UTE-MRIDual2nd echo and CTMediastinal, whereas the ground-glass component is imaged by UTE-MRIDual1st echo and CTlung with high accuracy. UTE-MRIDual predicts tumor invasiveness with 100% sensitivity and 87.5% specificity at a C/T threshold of 0.5.© 2023. The Author(s), under exclusive licence to European Society of Radiology.