目的是观察肿瘤手术后三叉神经病变的进展和结果。从2018年10月至2019年2月，我们进行了一项前瞻性观察性研究，纳入了25例肿瘤手术中确诊涉及三叉神经的患者。手术由高级作者执行。记录了术前和术后的三叉神经功能状态和临床数据。本研究包括18例脑膜瘤和7例三叉神经鞘瘤。在脑膜瘤患者中，55.6%的患者在手术前报告了面部感觉障碍，33.3%出现眼部不适，5.6%有咀嚼肌萎缩。术后，所有患者都出现了面部刺痛，94.4%的患者抱怨眼部干涩，有1例(5.56%)出现角膜炎。此外，有1例(5.56%)患者出现新发咀嚼肌无力。随访期间，50.0%的患者报告面部刺痛有所改善，1例(5.56%)出现恶化。眼部干涩症状在35.3%的患者中缓解，有1例患者观察到角膜炎缓解。然而，1例(5.56%)患者出现了神经营养性角膜炎。总体而言，55.6%的患者出现轻度咀嚼肌无力但无肌萎缩。在三叉神经鞘瘤病例中，28.6%的患者术前出现面部刺痛，42.9%出现眼部不适，1例(14.3%)抱怨咀嚼功能障碍。术后，85.7%的患者报告面部刺痛和眼部干涩，1例患者(16.7%)出现角膜炎。随访期间，66.7%的患者表现出面部刺痛改善，28.6%的患者眼部干涩症状缓解，1例患者(16.7%)从角膜炎中恢复。然而，1例(16.7%)患者出现新发神经营养性角膜炎。1例患者(16.7%)出现咀嚼功能缓解，但42.9%报告轻度恶化。另外1例患者(14.3%)面部麻木未见好转。手术后的三叉神经病变是一种常见的并发症，发生率高且恢复预后较差。当无法避免三叉神经损伤时，为了减轻术后三叉神经病变的严重影响，提供多学科和细致的随访，以及积极的管理策略是关键。© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.

To observe the evolution and outcomes of postoperative trigeminal neuropathy following surgery of tumor involving the trigeminal nerve.A prospective observational study was conducted between October 2018 and February 2019 involving 25 patients with tumors confirmed to involve the trigeminal nerve during surgery by senior author. Pre- and postoperative trigeminal nerve function status and clinical data were recorded.This study included 18 cases of meningioma and seven of trigeminal schwannoma. Among the meningioma cases, 55.6% of the patients reported facial sensory dysfunction before surgery, 33.3% presented ocular discomfort, and 5.6% had masticatory muscle atrophy. Postoperatively, all patients experienced facial paresthesia, 94.4% complained of eye dryness, and one (5.56%) exhibited keratitis. Additionally, one patient (5.56%) showed new-onset masticatory weakness. During follow-up, 50.0% of patients reported improvement in facial paresthesia, and one (5.56%) experienced deterioration. Eye dryness resolved in 35.3% of patients, and keratitis remission was observed in one patient. However, one patient (5.56%) developed neurotrophic keratitis. Overall, 55.6% of patients displayed mild masticatory weakness without muscle atrophy. In the cases of schwannoma, 28.6% of patients had facial paresthesia before surgery, 42.9% showed ocular discomfort, and one (14.3%) complained of masticatory dysfunction. Postoperatively, 85.7% of patients reported facial paresthesia and eye dryness, with one patient (16.7%) experiencing keratitis. During follow-up, 66.7% of patients demonstrated improvement in facial paresthesia, 28.6% showed eye dryness remission, and one patient (16.7%) recovered from keratitis. However, one patient (16.7%) developed new-onset neurotrophic keratitis. One patient (16.7%) experienced relief of masticatory dysfunction, but 42.9% reported mild deterioration. Another patient (14.3%) had facial anesthesia that had not improved.Postoperative trigeminal neuropathy is a common complication with a high incidence rate and poor recovery outcomes after surgery for tumors involving the trigeminal nerve. When trigeminal nerve damage is unavoidable, it is essential to provide a multidisciplinary and careful follow-up, along with active management strategy, to mitigate the more severe effects of postoperative trigeminal neuropathy.© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.