脑相关疾病是当今世界上最重要和最复杂的健康问题之一。这些脑相关疾病导致全球大量的疾病和死亡。然而，研究人员已经投入大量时间研究这些疾病，并取得了积极的结果；然而，当前可用于治疗这些疾病的药物数量相当有限。大黄素（EM）是一种多酚化合物，具有许多健康益处。它是从大黄根部提取的生物活性单体，具有抗炎、抗氧化、抗癌和神经保护性能。一系列临床前试验显示，EM对许多脑相关疾病具有保护作用。本综述根据多个临床前研究的结果，评估了EM作为治疗和管理各种脑相关疾病的药物的潜力，并考虑了该化合物的治疗性能。版权所有© Bentham Science Publishers；如有任何查询，请发送电子邮件至epub@benthamscience.net。

Brain-related disorders are one of the world's most important and complex health problems today. These brain-related disorders are responsible for a massive number of morbidities and death all around the world. However, researchers have devoted a large amount of time to investigating these diseases and found positive results; nevertheless, there are currently quite a few medications available to treat them. Emodin (EM), a polyphenol compound, has many health benefits. It is a biologically active monomer derived from rhubarb root that exhibits anti-inflammation, anti-oxidation, anticancer, and neuroprotective properties. A series of preclinical trials have shown EM to have protective benefits against many brain-related diseases. This review has evaluated the potential of EM as a pharmacological agent for the treatment and management of various brain-related disorders based on the findings of multiple pre-clinical studies and taking into account the compound's therapeutic properties.Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.