ABCA1是细胞内胆固醇转运至胞外的关键蛋白质，对降低周围组织中的胆固醇积累起着重要作用。文献计量学分析是通过数学和统计方法对各种文献进行定量分析的跨学科科学。它结合了学术出版物的结构和时间模式的分析，同时描述了主题集中度和不确定性类型。本文使用文献计量学方法分析了ABCA1的历史、热点和发展趋势。这将为读者提供ABCA1的研究现状和发展趋势，并帮助该领域的热点研究探索新的研究方向。经过筛选，ABCA1的研究在过去20年仍处于热点阶段。ABCA1正在涌现于之前无关的学科，如癌症。通过ABCA1，癌症与心血管疾病之间的关系得到了联系。本综述将指导不熟悉ABCA1研究的读者迅速了解ABCA1的发展过程，并为研究人员提供ABCA1未来可能的研究重点。版权所有 © 2023. Elsevier Inc. 发表。

ABCA1 is a key protein in the transport of intracellular cholesterol to the extracellular and plays an important role in reducing cholesterol accumulation in surrounding tissues. Bibliometric analysis refers to the cross-science of quantitative analysis of a variety of documents by mathematical and statistical methods. It combines an analysis of structural and temporal patterns in scholarly publications with a description of topic concentration and types of uncertainty. This paper analyzes the history, hotspot, and development trend of ABCA1 through bibliometrics. It will provide readers with the research status and development trend of ABCA1 and help the hot research in this field explore new research directions. After screening, the research on ABCA1 is still in a hot phase in the past 20 years. ABCA1 is emerging in previously unrelated disciplines such as cancer. There were 551 keywords and 6,888 breakout citations counted by Citespace. The relationship between cancer and cardiovascular disease has been linked by ABCA1. This review will guide readers who are not familiar with ABCA1 research to quickly understand the development process of ABCA1 and provide researchers with a possible future research focus on ABCA1.Copyright © 2023. Published by Elsevier Inc.