震颤性眼球运动和眼球快速颤动是一种特征性的注视性内插入，其特点是无间隔、相继发生、快速的眼球运动（注视）绕中线进行振荡。当此类运动仅在水平平面上发生时，被称为眼球快速颤动。当它在多个平面上发生（即水平、垂直和扭转）时，被称为震颤性眼球运动。最常见的病因类别是副感染性和副肿瘤性疾病。较少见的病因包括毒性代谢性、外伤性或特发性起源。这些运动的机制与脑干和小脑机制的功能失调有关，这些机制参与了注视的产生。在本综述中，我们讨论了震颤性眼球运动和眼球快速颤动的特点，描述了对患有震颤性眼球运动和眼球快速颤动的患者进行临床评估和管理的方法，并回顾了治疗干预的方法。最近的研究表明，仅在看左方时存在与眼位相关的震颤性眼球运动，这可能与额眼野或小脑蚓部结构的功能失调有关。震颤性眼球运动和眼球快速颤动起源于广泛的神经病理学，从神经解剖和病因学的角度都具有价值。版权所有 © 2023 Wolters Kluwer健康公司。保留所有权利。

Opsoclonus and ocular flutter are saccadic intrusions characterized by spontaneous, back-to-back, fast eye movements (saccades) that oscillate about the midline of central visual fixation without intervening inter-saccadic intervals. When this type of movement occurs exclusively in the horizontal plane, it is called ocular flutter. When it occurs in multiple planes (i.e. horizontal, vertical, and torsional) it is called opsoclonus. The most common etiologic categories are parainfectious and paraneoplastic diseases. Less common are toxic-metabolic, traumatic, or idiopathic origins. The mechanism of these movements relates to dysfunction of brainstem and cerebellar machinery involved in the generation of saccades. In this review, we discuss the characteristics of opsoclonus and ocular flutter, describe approaches to clinical evaluation and management of the patient with opsoclonus and ocular flutter, and review approaches to therapeutic intervention.Recent publications demonstrated eye position-dependent opsoclonus present only in left gaze, which may be related to dysfunction of frontal eye fields or structures in the cerebellar vermis.Opsoclonus and ocular flutter originate from a broad array of neuropathologies and have value from both a neuroanatomic and etiologic perspective.Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.