我们研究了在早期肝细胞癌患者中，少数民族医疗机构与非少数民族医疗机构的手术干预差异。我们还调查了手术管理与总体生存率之间的关联，按少数民族医疗机构的状态进行分层。我们在全国癌症数据库（2004-2018）中识别了早期肝细胞癌患者，定义为cT1。主要结果是手术干预（切除术、消融术或移植术）。确定了每个机构治疗的少数民族（非西班牙裔黑人或西班牙裔）患者的比例，并将前10%的机构视为少数民族医疗机构。 共有46,703例早期肝细胞癌患者被识别出来，其中4,214例（9.0%）在少数民族医疗机构接受治疗。相比于非少数民族医疗机构，少数民族医疗机构治疗的患者进行手术干预的可能性更低（奥数比 = 0.87, 95%置信区间：0.81-0.94）。在非少数民族医疗机构接受治疗的少数民族患者进行手术干预的可能性比白人患者更低（奥数比 = 0.86, 95%置信区间：0.82-0.90），而在少数民族医疗机构接受治疗的少数民族患者在手术干预的可能性上进一步降低（奥数比 = 0.81, 95%置信区间：0.69-0.94）。无论是少数民族医疗机构的状态如何，手术都与改善总体生存率有关。无论在少数民族医疗机构还是非少数民族医疗机构，接受手术的白人和少数民族患者的总体生存率没有临床意义上的差异。 早期肝细胞癌患者在接受少数民族医疗机构的治疗时，手术干预的可能性降低。在少数民族医疗机构接受治疗的少数民族患者的手术干预可能性降低，但在非少数民族医疗机构接受治疗时程度较小。无论是否为少数民族或少数民族医疗机构状态，手术与改善总体生存率有关。 版权所有 © 2023 Elsevier Inc. 保留所有权利。

We examined differences in surgical intervention at minority-serving hospitals versus non-minority-serving hospitals among patients with early-stage hepatocellular carcinoma. We also investigated associations between surgical management and overall survival, stratified by minority-serving hospital status.Patients with early-stage hepatocellular carcinoma, defined as cT1, were identified within the National Cancer Database (2004-2018). The primary outcome was surgical intervention (resection, ablation, or transplantation). The proportion of minority (non-Hispanic Black or Hispanic) patients treated at each facility was determined, and hospitals in the top decile were considered minority-serving hospitals.A total of 46,703 patients with early-stage hepatocellular carcinoma were identified, of whom 4,214 (9.0%) were treated at minority-serving hospitals. Patients treated at minority-serving hospitals were less likely to undergo surgical intervention than patients treated at non-minority-serving hospitals (odds ratio = 0.87, 95% confidence interval: 0.81-0.94). Minority patients treated at non-minority-serving hospitals were less likely to undergo surgical intervention than White patients (odds ratio = 0.86, 95% confidence interval: 0.82-0.90) and had a further associated decrease in the likelihood of surgical intervention when treated at minority-serving hospitals (odds ratio = 0.81, 95% confidence interval: 0.69-0.94). Regardless of minority-serving hospital status, surgery was associated with improved overall survival. There were no clinically meaningful differences in overall survival between White and minority patients who underwent surgery either at minority-serving hospitals or non-minority-serving hospitals.Patients with early-stage hepatocellular carcinoma had an associated decrease in the likelihood of surgical intervention when treated at minority-serving hospitals. Minority patients treated at minority-serving hospitals had an associated decrease in the likelihood of surgery, but to a lesser extent when treated at non-minority-serving hospitals. Surgery was associated with improved overall survival regardless of minority or minority-serving hospital status.Copyright © 2023 Elsevier Inc. All rights reserved.