本研究旨在检查胰腺癌诊断后早期与晚期姑息护理转诊（PCR）的影响。在一所主要的学术机构，确定了2014年至2020年接受PCR的PDAC患者。根据确诊时间，将PCR分为早期（< 30天）和晚期（≥30天）。获取了急诊科就诊次数、重症监护室（ICU）收治次数和住院次数的数据。在1458名PDAC患者中，有419名（28.7%）接受了PCR，其中67.3%（n = 282）接受了晚期PCR。接受PCR的大多数患者是白人（85%）和男性（54.8%），诊断时的中位年龄为62岁。接受早期PCR的患者在诊断时更常见为第4分期（早期：n = 91，69% vs. 晚期：n = 132，47%），而接受晚期PCR的患者更常见为第1到第3分期（早期：n = 40，30.5% vs. 晚期：n = 150，53.2%）（p < 0.001）。与接受晚期PCR的患者相比，接受早期PCR的患者的急诊科就诊中位数（1次 vs. 2次，p < 0.001）和住院次数（1次 vs. 2次，p < 0.001）较少。然而，在进行复发事件Cox比例风险模型分析后，PCR的时间对住院没有影响（HR 0.88，95% CI 0.68, 1.14；p = 0.3）。PDAC患者PCR的时机与卫生保健利用率无关。需要进一步进行前瞻性试验来研究姑息护理服务早期融入多学科胰腺癌团队的以患者为中心的影响。© 2023. 作者，独家许可给德国施普林格出版社，施普林格自然出版集团的一部分。

The purpose of this study was to examine the impact of early versus late palliative care referral (PCR) following pancreatic cancer diagnosis.Patients diagnosed with PDAC who received a PCR between 2014 and 2020 at a major academic institution were identified. PCR was classified as early (< 30 days) or late (≥ 30 days) based on time from definitive diagnosis. Data were obtained on number of emergency department (ED) visits, intensive care unit (ICU) admissions, and hospital admissions.Among 1458 patients with PDAC, 419 (28.7%) received PCR, among which 67.3% (n = 282) received a late PCR. Of those who received PCR, the majority were White (85%) and male (54.8%), with a median age of 62 years at time of diagnosis. Patients who received an early PCR more commonly presented with stage 4 disease at diagnosis (early: n = 91, 69% vs. late: n = 132, 47%), whereas patients who received a late PCR more commonly presented with stage 1, 2, or 3 disease (early: n = 40, 30.5% vs. late: n = 150, 53.2%) (p < 0.001). Patients who received early PCR had fewer median ED visits (1 vs. 2, p < 0.001) and hospital admissions (1 vs. 2, p < 0.001) compared with patients who received late PCR. However, after performing recurrent-event Cox-proportional hazards models, the timing of PCR did not impact hospital admission (HR 0.88, 95% CI 0.68, 1.14; p = 0.3).Timing of PCR for patients with PDAC was not associated with healthcare utilization. Further prospective trials are needed to study the patient-centered impact of early integration of palliative care services into multidisciplinary pancreatic cancer teams.© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.