研究动态
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监测干细胞和器官样体在三维环境中增殖的光谱技术,用于治疗研发的研究。

Spectroscopic Techniques for Monitoring Stem Cell and Organoid Proliferation in 3D environments for Therapeutic Development.

发表日期:2023 Aug 22
作者: Wei Mao, Hoai-Thuong Duc Bui, Wanho Cho, Hyuk Sang Yoo
来源: ADVANCED DRUG DELIVERY REVIEWS

摘要:

干细胞与器官样体的增殖监测领域中,光谱技术引起了重要的治疗发展关注。荧光、拉曼光谱和红外光谱等光谱技术提供了在干细胞与器官样体增殖过程中发生的生化与生物物理变化的无创和实时监测。这些技术为研究潜在治疗药物作用的基本机制提供了有价值的洞察,有助于改进药物发现和筛选。本综述强调了光谱监测干细胞和器官样体增殖的重要性,以及其对治疗发展的潜在影响。此外,本综述还讨论了光谱技术在干细胞和器官样体研究中的最新进展及其应用。总的来说,本综述强调了光谱技术作为研究干细胞和器官样体增殖的有价值工具,以及其在未来改革治疗发展方面的潜力。版权所有 © 2023. Elsevier B.V. 发表。
Spectroscopic techniques for monitoring stem cell and organoid proliferation have gained significant attention in therapeutic development. Spectroscopic techniques such as fluorescence, Raman spectroscopy, and infrared spectroscopy offer noninvasive and real-time monitoring of biochemical and biophysical changes that occur during stem cell and organoid proliferation. These techniques provide valuable insight into the underlying mechanisms of action of potential therapeutic agents, allowing for improved drug discovery and screening. This review highlights the importance of spectroscopic monitoring of stem cell and organoid proliferation and its potential impact on therapeutic development. Furthermore, this review discusses recent advances in spectroscopic techniques and their applications in stem cell and organoid research. Overall, this review emphasizes the importance of spectroscopic techniques as valuable tools for studying stem cell and organoid proliferation and their potential to revolutionize therapeutic development in the future.Copyright © 2023. Published by Elsevier B.V.