在初级医疗中心中针对新出现的呼吸困难或咯血病例进行的及时胸部影像学指南一致性研究:一项回顾性队列研究。
Guideline concordance for timely chest imaging after new presentations of dyspnoea or haemoptysis in primary care: a retrospective cohort study.
发表日期:2023 Aug 24
作者:
Minjoung Monica Koo, Luke T A Mounce, Meena Rafiq, Matthew E J Callister, Hardeep Singh, Gary A Abel, Georgios Lyratzopoulos
来源:
HEART & LUNG
摘要:
生物和医学领域的科学家通常精通英语和简体中文。请将以下段落准确地翻译成简化的中文,符合学术论文的语言模式,并保持原文的结构:
指南建议对新出现呼吸困难或咯血的患者进行紧急胸部X光检查,但对其执行情况的证据很少。我们分析了2012年4月至2017年3月期间在初级保健中心报道的30岁及以上新出现呼吸困难或咯血患者的关联初级保健和医院影像数据。我们使用Logistic回归分析,检查了符合指南的管理情况,其定义为症状出现后2周内由家庭医生进行的胸部X光/CT检查,以及社会人口特征和相关病史的差异。此外,在被诊断为癌症的患者中,我们还描述了符合指南的状态下的诊断时间、诊断途径和诊断阶段。
总共,有22,560/162,161(13.9%)的呼吸困难患者和4,022/8120(49.5%)的咯血患者在推荐的2周期限内接受了符合指南的影像检查。有近期胸部影像的患者更不可能接受影像检查(调整后的OR 0.16,95% CI: 0.14-0.18适用于呼吸困难,调整后的OR 0.09, 95% CI 0.06-0.11适用于咯血)。慢性阻塞性肺疾病/哮喘的病史也与指南一致性的几率较低相关(呼吸困难:OR 0.234, 95% CI 0.225-0.242,咯血:0.88, 0.79-0.97)。呼吸困难患者中有先前心力衰竭史、吸烟史或已戒烟者以及较贫穷的社会经济群体的几率更低。
遵守指南的影像检查组在12个月内被诊断为肺癌的几率更大(呼吸困难:1.1% vs 0.6%;咯血:3.5% vs 2.7%)。接受紧急影像检查的几率与随后诊断为癌症的风险一致。然而,尽管符合资格,但仍有相当比例的呼吸困难和咯血患者没有及时接受胸部影像检查,这表明了早期诊断肺癌的机会。
© 作者(或其雇主)2023年。在CC BY许可下再使用。由BMJ发布。
Guidelines recommend urgent chest X-ray for newly presenting dyspnoea or haemoptysis but there is little evidence about their implementation.We analysed linked primary care and hospital imaging data for patients aged 30+ years newly presenting with dyspnoea or haemoptysis in primary care during April 2012 to March 2017. We examined guideline-concordant management, defined as General Practitioner-ordered chest X-ray/CT carried out within 2 weeks of symptomatic presentation, and variation by sociodemographic characteristic and relevant medical history using logistic regression. Additionally, among patients diagnosed with cancer we described time to diagnosis, diagnostic route and stage at diagnosis by guideline-concordant status.In total, 22 560/162 161 (13.9%) patients with dyspnoea and 4022/8120 (49.5%) patients with haemoptysis received guideline-concordant imaging within the recommended 2-week period. Patients with recent chest imaging pre-presentation were much less likely to receive imaging (adjusted OR 0.16, 95% CI 0.14-0.18 for dyspnoea, and adjusted OR 0.09, 95% CI 0.06-0.11 for haemoptysis). History of chronic obstructive pulmonary disease/asthma was also associated with lower odds of guideline concordance (dyspnoea: OR 0.234, 95% CI 0.225-0.242 and haemoptysis: 0.88, 0.79-0.97). Guideline-concordant imaging was lower among dyspnoea presenters with prior heart failure; current or ex-smokers; and those in more socioeconomically disadvantaged groups.The likelihood of lung cancer diagnosis within 12 months was greater among the guideline-concordant imaging group (dyspnoea: 1.1% vs 0.6%; haemoptysis: 3.5% vs 2.7%).The likelihood of receiving urgent imaging concords with the risk of subsequent cancer diagnosis. Nevertheless, large proportions of dyspnoea and haemoptysis presenters do not receive prompt chest imaging despite being eligible, indicating opportunities for earlier lung cancer diagnosis.© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.